Browsing Medical Bioscience by Title
Now showing items 191-210 of 280
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Oral colonization of Gram-negative anaerobes as a risk factor for preterm birth
(Landes Bioscience, 2011)Preterm birth significantly impacts on neonatal morbidity and mortality and is apparently increasing worldwide. Several studies have attempted to define a causative role for periodontal disease in adverse pregnancy ... -
Oral health status and treatment needs of pregnant women attending antenatal clinics in KwaZulu-Natal, South Africa
(Hindawi, 2019)During pregnancy, the oral cavity is characterised by an acidic environment and an inflammatory response brought about by vomiting and changes in hormonal levels, respectively, thereby increasing the mother’s risk of ... -
Origin, Migration, and Reproduction of Indigenous Domestic Animals with Special Reference to Their Sperm Quality
(MDPI, 2022): Indigenous domestic animals such as cattle, sheep, goats, pigs, and chickens have a natural resistance to endo- and ecto-parasites and are tolerant in terms of harsh environmental conditions. These species orginated ... -
Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells
(Elsevier, 2006)The genome of the severe acute respiratory syndrome coronavirus encodes for eight accessory viral proteins with no known homologues in other coronaviruses. One of these is the 3b protein, which is encoded by the second ... -
Overexpression of 7a, a Protein Specifically Encoded by the Severe Acute Respiratory Syndrome Coronavirus, Induces Apoptosis via a Caspase-Dependent Pathway
(American Society for Microbiology, 2004)Besides genes that are homologous to proteins found in other coronaviruses, the severe acute respiratory syndrome coronavirus genome also contains nine other potential open reading frames. Previously, we have characterized ... -
Overview of the effects of moringa oleifera leaf extract on oxidative stress and male infertility: a review
(MDPI, 2023)According to a recent report by the WHO, 50–80 million people suffer with infertility. Amongst these populations, male counterparts account for 20–50% of infertility cases. The aetiology of infertility in men includes many ... -
Oxidative stress and assisted reproduction: A comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment
(MDPI, 2022)Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and antioxidants has been established as an important factor that can negatively affect the outcomes of assisted reproductive techniques ... -
Oxidative stress: A comprehensive review of biochemical, molecular, and genetic aspects in the pathogenesis and management of varicocele
(Korean Society for Sexual Medicine and Andrology, 2021)Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its primary edition, 40 years ago. ... -
The paracrine effect of hypoxic and normoxic cancer secretion on the proliferation of brain endothelial cells (bend.3)
(MDPI, 2022): Background: This study aimed to investigate the disruption of cell cycle phases of bEnd.3 cells exposed to cancer paracrine secretion. Cancer cells have been reported to use the secretion of paracrine factors to ... -
The pathophysiology of rhabdomyolysis in ungulates and rats: towards the development of a rodent model of capture myopathy
(Springer, 2023)Capture myopathy (CM), which is associated with the capture and translocation of wildlife, is a life-threatening condition that causes noteworthy morbidity and mortality in captured animals. Such wildlife deaths have a ... -
PICSI vs. MACS for abnormal sperm DNA fragmentation ICSI cases: A prospective randomized trial
(Springer Nature, 2020)Purpose: To know which sperm selection technique, physiological intracytoplasmic sperm injection (PICSI) or magnetic-activated cell sorting (MACS), is better for the selection of sperm with abnormal sperm DNA fragmentation ... -
A plant-produced SARS-CoV-2 spike protein elicits heterologous immunity in hamsters
(Frontiers Media, 2023)Molecular farming of vaccines has been heralded as a cheap, safe and scalable production platform. In reality, however, differences in the plant biosynthetic machinery, compared to mammalian cells, can complicate the ... -
Polymorphisms of androgens-related genes and idiopathic male infertility in Turkish men
(Wiley, 2021)Androgens, testosterone and dihydrotestosterone (DHT) are endocrine regulators of spermatogenesis and act via androgen receptor (AR). The aim of this study was to investigate the association(s) of AR (CAG repeat length), ... -
A population model for the 2017/18 listeriosis outbreak in South Africa
(PLoS One, 2020-03-12)We introduce a compartmental model of ordinary differential equations for the population dynamics of listeriosis, and we derive a model for analysing a listeriosis outbreak. The model explicitly accommodates neonatal ... -
Potential for increasing folate contents of traditional African fermented sorghum gruel (Motoho) using presumptive probiotic lactic acid bacteria
(Elsevier, 2023)Folate deficiency is commonly observed in most developing countries. Lactic acid bacteria (LAB) fermentation of cereal-based foods could be an alternative to improving folate intake. This study evaluated the possibility ... -
Preliminary study on the effect of sugar cane (Saccharum officinarum) molasses on steroidogenesis in testicular cell cultures
(Academic Journals, 2010)Blackstrap molasses has been used for centuries in the preparation of food products and have also been used to treat numerous ailments such as high blood pressure, arthritis, ulcers, dermatitits, eczema, constipation, ... -
Preservation of shortening velocity and power output in single muscle fibres from patients with idiopathic inflammatory myopathies
(Springer, 2022)Idiopathic inflammatory myopathies (IIMs) are autoimmune disorders of skeletal muscle causing weakness and disability. Utilizing single fibre contractility studies, we have previously shown that contractility is affected ... -
Profiles of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers
(American Society for Microbiology, 2004) -
Protein profiling in unlocking the basis of varicocele-associated infertility
(Blackwell Publishing Ltd, 2021)Varicocele is one of the major causes of male infertility and has a negative impact on spermatogenesis. The conventional semen analysis does not reveal the underlying subcellular mechanisms associated with defects in ... -
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ...