Now showing items 208-227 of 277

    • Proteomics and metabolomics — Current and future perspectives in clinical andrology 

      Henkel, R; Panner, Selvam M.K; Finelli, R (Blackwell Publishing Ltd, 2021)
      Proteomics and metabolomics are emerging as promising tools to investigate the molecular mechanisms associated with male infertility. Proteins and metabolites play a pivotal role in regulating the molecular pathways ...
    • Proteomics of drug-resistant HIV-associated candidiasis 

      Abrantes, Pedro Miguel dos Santos; Bouic, Patrick J.D.; Africa, Charlene W.J. (University of the Western Cape, 2015)
      Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ...
    • Psychosocial reintegration following traumatic spinal cord injury in South Africa: The influence of employment, injury characteristics and living situation 

      Nizeyimana, Eugene; Phillips, Joliana; Joseph, Conran (The Journal of Spinal Cord Medicine,, 2022)
      1Department of Health and Rehabilitation Sciences, Division of Physiotherapy, Stellenbosch University, Cape Town, South Africa, 2Department of Physiotherapy, University of the Western Cape, Cape Town, South Africa Objectives: ...
    • Quantification and identification of sperm subpopulations using computer-aided sperm analysis and species-specific cut-off values for swimming speed 

      Maree, Liana; van der Horst, Gerhard (Taylor & Francis, 2013)
      Motility is an essential characteristic of all fl agellated spermatozoa and assessment of this parameter is one criterion for most semen or sperm evaluations. Computer-aided sperm analysis (CASA) can be used to measure ...
    • Quantitative assessment of heavy metal effects on sperm function using computer‐aided sperm analysis and cytotoxicity assays 

      Hardneck, Farren; Israel, Gadieja; Pool, Edmund; Maree, Liana (Wiley, 2018)
      One known environmental risk factor impacting on human reproduction is heavy metal pollution. Although some metals (e.g., Cu, Se and Zn) have protective effects on the male reproductive system in low doses, heavy metals ...
    • Quantitative sperm characteristics of Tankwa goats with special reference to hyperactivated motility 

      Ngcauzele, Asanele; van der Horst, Gerhard; Kotze, A (South African Society for Animal Science, 2020)
      Computer-assisted semen analysis (CASA) is an automated and objective method of evaluating structural (e.g. morphology) and functional sperm parameters (e.g. motility and hyperactivation). Sperm hyperactivation is essential ...
    • Quest for the best—a move to anatomical endoscopic enucleation of the prostate 

      Henkel, Ralf; Cho, Chaklam; Teoh, Jeremy Yuen Chun (Wiley-Blackwell, 2020)
      The history of surgical enucleation for the treatment of lower urinary tract symptoms caused by benign prostatic enlargement dates back more than 100 years (Freyer, 1919). Open prostatec-tomy (OP) is an invasive procedure ...
    • Radiations and male fertility 

      Kesari, Kavindra Kumar; Agarwal, Ashok; Henkel, Ralf (Springer Nature, 2018)
      During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat ...
    • Radiosensitization effect of gold nanoparticles in proton therapy 

      Cunningham, C.; De Kock, M.; Engelbrecht, M.; Miles, X. (Frontiers Media, 2021)
      The number of proton therapy facilities and the clinical usage of high energy proton beams for cancer treatment has substantially increased over the last decade. This is mainly due to the superior dose distribution of ...
    • Rare fungal species isolated from Libyan diabetic patients 

      Esmaio, Mustafa; Abrantes, Pedro Miguel dos Santos; Africa, Charlene W.J. (Infection Control Africa Network (ICAN), 2016)
      BACKGROUND AND OBJECTIVES: The emerging resistance of Candida species to antifungals routinely used to treat candidiasis in HIV patients and in patients with diabetes mellitus (DM) has resulted in the frequent isolation ...
    • Reactive oxygen species and male reproductive hormones 

      Darbandi, Mahsa; Darbandi, Sara; Agarwal, Ashok; Sengupta, Pallav; Durairajanayagam, Damayanthi; Henkel, Ralf; Sadeghi, Mohammad Reza (BMC, 2018)
      Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ...
    • Reactive oxygen species and male reproductive hormones 

      Darbandi, Mahsa; Darbandi, Sara; Agarwal, Ashok; Sengupta, Pallav; Durairajanayagam, Damayanthi; Henkel, Ralf; Sadeghi, Mohammad Reza (BMC, 2018)
      Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ...
    • Reactive oxygen species in male reproduction: A boon or a bane? 

      Henkel, R; Baskaran, S; Finelli, R (Blackwell Publishing Ltd, 2021)
      Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
    • Reactive oxygen species in male reproduction: A boon or a bane? 

      Finelli, Renata; Henkel, Ralf; Baskaran, Saradha (Wiley, 2020)
      Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
    • Real-time assessment of Candida biofilm disruption by Galenia africana 

      Stuurman, Keith; Abrantes, Pedro Miguel dos Santos; Klaasen, Jeremy; Africa, Charlene Wilma Joyce (2022-05-25)
      Candida species often cause opportunistic infections in immunocompromised patients and are able to form highly structured biofilms that protect the yeast cells from the external environment and the action of antimicrobials. ...
    • Real-time assessment of Candida biofilm formation 

      Abrantes, Pedro Miguel dos Santos; Behardien, Kauthar; Africa, Charlene Wilma Joyce (Elsevier, 2021-09)
      Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, particularly when the Candida biofilm is composed of drug-resistant species. Although the biofilm formation ...
    • Real-time assessment of interspecies candida biofilm formation 

      Abrantes, Pedro MDS; Behardien, Kauthar; Africa, Charlene WJ (Bentham Open, 2022-12-30)
      Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, with Candida having the ability to form highly structured biofilms that protect them from the external ...
    • Reconstruction of major maternal and paternal lineages of the Cape Muslim population 

      Isaacs, Shafieka; Geduld-Ullah, Tasneem; Benjeddou, Mongi (Sociedade Brasileira de Genética, 2013)
      The earliest Cape Muslims were brought to the Cape (Cape Town - South Africa) from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they ...
    • Records of ctenophores from South Africa 

      Gibbons, M.J; Haddock, S.H.D; Matsumoto, G.I (PeerJ Inc., 2021)
      Although ctenophores can be conspicuous components of the plankton in coastal marine ecosystems, only six species have been formally described from around South Africa. Using photographs from local community scientists, ...
    • Regulation of AKT/AMPK signaling, autophagy and mitigation of apoptosis in Rutin-pretreated SH-SY5Y cells exposed to MPP+ 

      Enogieru, A.B; Haylett, W; Hiss, D.C (Springer Nature, 2021)
      Accumulating evidence suggest that apoptosis, autophagy and dysregulation of signaling pathways are common mechanisms involved in Parkinson’s disease (PD) pathogenesis, and thus development of therapeutic agents targeting ...