Browsing Medical Bioscience by Title
Now showing items 52-71 of 277
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A comparison between the anthropological and modern day uses of this indigenous herb
(Conference: SA Medical Research Council 6th Annual Research Conference, 2012)Sceletium tortuosum (Fig. 1) is a scrambling succulent ground cover indigenous to the Western and Eastern Cape. It has probably been used for centuries as a mood-altering drug, especially by the Khoisan hunters and Nama ... -
A comparison of susceptibility patterns of oral Candida isolates from South African and Cameroonian HIV- positive populations
(The International Association for Dental Research (IADR), 2012)METHOD: In this study, Candida isolates were collected from the oral mucosa of 128 South African and 126 Cameroonian HIV-positive patients, by scraping the mouths of consenting patients using sterile cotton swabs. Ethics ... -
Contaminants of emerging concern (cecs) and male reproductive health: Challenging the future with a double-edged sword
(MDPI, 2023)Approximately 9% of couples are infertile, with half of these cases relating to male factors. While many cases of male infertility are associated with genetic and lifestyle factors, approximately 30% of cases are still ... -
Controversy and consensus on indications for sperm dna fragmentation testing in male infertility: a global survey, current guidelines, and expert recommendations
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of the World Health Organization laboratory manual for the examination and processing of human semen. Many conditions and risk factors ... -
The Coronavirus Nucleocapsid is a Multifunctional Protein
(MDPI, 2014)The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic RNA, interacts with the viral membrane protein during virion assembly and plays a critical role in enhancing the efficiency of virus ... -
Corrigendum: Immunological changes during space travel: A ground-based evaluation of the impact of neutron dose rate on plasma cytokine levels in human whole blood cultures
(Frontiers Media, 2021)A better understanding of the combined impact of different space stressors on human health is urgently warranted, considering the upcoming long-duration missions beyond lower Earth orbit. Therefore, a growing number of ... -
Cost of Traditional Herbal Medicines for Noncommunicable Diseases in Rural and Urban Communities in South Africa
(Elsevier Inc., 2022)Objectives: This study assessed traditional herbal medicine (THM) and conventional medicine (CM) utilization among par- participants with a noncommunicable diseases in South Africa. Methods: A cross-sectional study of the ... -
Criteria to facilitate the implementation of woman-centred care in childbirth units of Limpopo Province, South Africa (Part 2)
(OASIS OpenJournals, 2013)Background: Facilitation of mutual participation, respectful and egalitarian relationship between the mother and the midwife during childbirth is a critical aspect. This article delineated the criteria that would facilitate ... -
Critical evaluation of two models of flow cytometers for the assessment of sperm DNA fragmentation: an appeal for performance verification
(Medknow Publications, 2019)Lack of standardized, reproducible protocols and reference values is among the challenges faced when using new or upgraded versions of instruments in reproductive laboratories and flow cytometry. Terminal deoxynucleotidyl ... -
Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves
(BMC, 2019)The plant Holarrhena floribunda (H. floribunda; G. Don) is indigenous to sub-Saharan Africa and is traditionally used to treat several ailments. The present study was carried out to isolate and characterize bioactive ... -
Data Management Plans in the genomics research revolution of Africa: Challenges and Recommendations
(Elsevier, 2021)Drafting and writing a data management plan (DMP) is increasingly seen as a key part of the academic research process. A DMP is a document that describes how a researcher will collect, document, describe, share, and preserve ... -
Determination of seminal oxidation–reduction potential (ORP) as an easy and cost-effective clinical marker of male infertility
(Wiley, 2017)Oxidative stress (OS) is an important contributing factor to male infertility. While previous methods to measure seminal OS are time-consuming and limited to the use of freshly produced semen, oxidation reduction potential ... -
Development of molecular tools for honeybee virus research: the South African contribution
(Academic Journals, 2003)Increasing knowledge of the association of honeybee viruses with other honeybee parasites, primarily the ectoparasitic mite Varroa destructor, and their implication in the mass mortality of honeybee colonies has resulted ... -
Diagnostic value of advanced semen analysis in evaluation of male infertility
(Blackwell Publishing Ltd, 2021)Conventional semen analysis is the standard of care to initially evaluate the fertility status of a male patient. However, it has some limitations and among these are failure to correctly identify the aetiology underlying ... -
Diagnostic value of routine semen analysis in clinical andrology
(Blackwell Publishing Ltd, 2021)Infertility is a major health issue affecting over 48.5 million couples around the world, with the male factor accounting for about 50% of the cases. The conventional semen analysis recommended by the World Health Organization ... -
Differential effects of normoxic versus hypoxic derived breast cancer paracrine factors on brain endothelial cells
(MPDI, 2021)The blood-brain barrier (BBB) is a central nervous system protective barrier formed primarily of endothelial cells that regulate the entry of substances and cells from entering the brain. However, the BBB integrity is ... -
Differential sensitivity of two endothelial cell lines to hydrogen peroxide toxicity: Relevance for in vitro studies of the blood–brain barrier
(MPDI, 2020)Oxidative stress (OS) has been linked to blood–brain barrier (BBB) dysfunction which in turn has been implicated in the initiation and propagation of some neurological diseases. In this study, we profiled, for the first ... -
A diverse array of genetic factors contribute to the pathogenesis of Systemic Lupus Erythematosus
(Biomed Central, 2013)Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with variable clinical presentation frequently affecting the skin, joints, haemopoietic system, kidneys, lungs and central nervous system. It can ... -
Do lifestyle practices impede male fertility?
(John Wiley & Sons, Inc, 2020)Alongside an increasing prevalence of couple and male infertility, evidence suggests there is a global declining trend in male fertility parameters over the past few decades. This may, at least in part, be explained ... -
Drug susceptibility profiles of Candida species isolated from the oral mucosa of HIV-positive West African patients using the TREK Sensititre system
(2013)BACKGROUND: Candida infections are a common cause of death in immunocompromised patients. The prevalence and anti-mycotic drug susceptibility profiles of Candida species from Cameroon in Africa are unavailable. This ...