Browsing Medical Bioscience by Author "Choi, Yook-Wah"
Now showing items 1-3 of 3
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Cellular Characterization of SARS Coronavirus Nucleocapsid
Goh, Phuay-Yee; Choi, Yook-Wah; Shen, Shuo; Tan, Yee-Joo; Fielding, Burtram C.; Tan, Timothy H.P.; O, Eng-Eong; Lim, Seng Gee; Hong, Wanjin (Leibniz Research Centre for Working Environment and Human Factors, 2004)The Severe and Acute Respiratory Syndrome coronavirus (SARS CoV) is a newly-emerged virus that caused an outbreak of atypical pneumonia in the winter of 2002-2003. Polyclonal antibodies raised against the nucleocapsid (N) ... -
Expression, purification and preliminary crystallographic analysis of recombinant human DEAD-box polypeptide 5
Choi, Yook-Wah; Dutta, Sujit; Fielding, Burtram C.; Tan, Yee-Joo (International Union of Crystallography, 2010)The DEAD-box RNA helicase DDX5 is involved in many aspects of RNA processing and has been implicated in a number of cellular processes involving alteration of RNA secondary structure. The N-terminal region of DDX5, ... -
The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus
Dutta, Sujit; Gupta, Garvita; Choi, Yook-Wah; Kotaka, Masayo; Fielding, Burtram C.; Song, Jianxing; Tan, Yee-Joo (Portland Press, 2012)RNA helicases of the DEAD (Asp-Glu-Ala-Asp)-box family of proteins are involved in many aspects of RNA metabolism from transcription to RNA decay, but most of them have also been shown to be multifunctional. The DEAD-box ...