Browsing Medical Bioscience by Author "Fisher, David"
Now showing items 1-8 of 8
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Carica papaya seed extract slows human sperm
Ghaffarilaleh, Vahid; Fisher, David; Henkel, Ralf (Elsevier, 2019)Ethnopharmacological relevance: Traditional healers use Carica papaya seeds as a remedy for diseases and as a contraceptive for men and abortion in women. Material and methods: Semen samples from 35 healthy men were allowed ... -
Differential effects of normoxic versus hypoxic derived breast cancer paracrine factors on brain endothelial cells
Rado, Mariam; Flepisi, Brian; Fisher, David (MPDI, 2021)The blood-brain barrier (BBB) is a central nervous system protective barrier formed primarily of endothelial cells that regulate the entry of substances and cells from entering the brain. However, the BBB integrity is ... -
Exosomes form tunneling nanotubes (TUNTs) in the blood-brain barrier: A nano-anatomical perspective of barrier genesis
Mentor, Shireen; Fisher, David (Frontiers Media, 2022)The blood-brain barrier (BBB) is a robust interface between the blood and the central nervous system. Barrier type endothelium is able to limit paracellular (PC) movement, relegating molecular flux to the transendothel ... -
Face-to-face versus online-based lectures: A covid-19 induced study on assessments
Fisher, David; Solomons, Deon; Makhathini, Khayelihle Brian (Frontiers Media, 2022)There is much debate regarding the impact of COVID-induced lockdown on the standard of assessments, mainly since students were assessed at home via an online assessment platform. Regular orthodox lectures and assessments ... -
High-resolution insights into the in vitro developing blood-brain barrier: Novel morphological features of endothelial nanotube function
Mentor, Shireen; Fisher, David (Frontiers Media, 2021)High-resolution electron microscopy (HREM) imaging of the in vitro blood-brain barrier (BBB), is a promising modality for investigating the dynamic morphological interplay underpinning BBB development. The successful ... -
The Ism between endothelial cilia and endothelial nanotubules is an evolving concept in the genesis of the BBB
Mentor, Shireen; Fisher, David (MDPI, 2022)The blood–brain barrier (BBB) is fundamental in maintaining central nervous system (CNS) homeostasis by regulating the chemical environment of the underlying brain parenchyma. Brain endothelial cells (BECs) constitute ... -
The paracrine effect of hypoxic and normoxic cancer secretion on the proliferation of brain endothelial cells (bend.3)
Rado, Mariam; Fisher, David (MDPI, 2022): Background: This study aimed to investigate the disruption of cell cycle phases of bEnd.3 cells exposed to cancer paracrine secretion. Cancer cells have been reported to use the secretion of paracrine factors to ... -
The relationship between seminal leukocytes, oxidative status in the ejaculate, and apoptotic markers in human spermatozoa
Mupfiga, Cleyson; Fisher, David; Kruger, Thinus; Henkel, Ralf (Taylor & Francis, 2013)The aim of this study was to investigate the relationship between seminal leukocytes, reactive oxygen species (ROS) production in the ejaculate, and markers of apoptosis in human spermatozoa. Semen samples were collected ...