Browsing Research Articles (Medical Bioscience) by Author "Henkel, Ralf"
Now showing items 21-40 of 55
-
Impact of body composition analysis on male sexual function: A metabolic age study
Majzoub, Ahmad; Elbardisi, Haitham; Henkel, Ralf (Frontiers Media, 2023)Metabolic Age (MetAge) and body composition analysis may reflect an individual’s metabolic status, which is believed to influence male sexual and gonadal functions. Although erectile dysfunction (ED) and hypogonadism ... -
The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment
Lewis, Sheena E.M.; Aitken, R. John; Conner, Sarah J.; De Iuliis, Geoffry; Evenson, Donald P.; Henkel, Ralf; Giwercman, Aleksander; Gharagozloo, Parviz (Elsevier, 2013)Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo quality and pregnancy rates, and higher ... -
Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis
Ashok, Agarwal; Cannarella, Rossella; Henkel, Ralf; Raghavender, Kosgi (Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Despite the significant role of varicocele in the pathogenesis of male infertility, the impact of varicocele repair (VR) on conventional semen parameters remains controversial. Only a few systematic reviews and ... -
In Silico Sperm Proteome Analysis to Investigate DNA Repair Mechanisms in Varicocele Patients
Henkel, Ralf; Finelli, R; Darbandi, S; Pushparaj, P. N.; Ko, E.; Agarwal, A. (Frontiers Media S.A., 2021-12-17)Varicocele, a condition associated with increased oxidative stress, negatively affects sperm DNA integrity and reduces pregnancy rates. However, the molecular mechanisms related to DNA integrity, damage, and repair in ... -
In vitro effects of aqueous extract of unfermented rooibos on human spermatozoa
Henkel, Ralf; Takalani, Ndivhuho; Gbenga, Adefolaju; Chinyerum, Opuwari (Wiley, 2022)The inability to conceive is a baleful experience for thousands of couples worldwide. Among different well-known reproductive techniques, medicinal plants have been utilized to treat male infertility. Medicinal plants, ... -
In vivo effects of eurycoma longifolia Jack (Tongkat Ali) extract on reproductive functions in the rat
Solomon, Michael; Erasmus, N.; Henkel, Ralf (Blackwell, 2013)An aqueous extract of Eurycoma longifolia (Tongkat Ali; TA) roots is traditionally used to enhance male sexuality. Because previous studies are limited to only few sperm parameters or testosterone concentration, this study ... -
An in-depth bibliometric analysis and current perspective on male infertility research
Baskaran, Saradha; Agarwal, Ashok; Leisegang, Kristian; Peter, Natesan Pushparaj; Selvam, Manesh Kumar Panner; Henkel, Ralf (Korean Society for Sexual Medicine and Andrology, 2019)PURPOSE: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to analyze male infertility research ... -
Interpretation of semen analysis using WHO 1999 and WHO 2010 reference values: abnormal becoming normal
Alshahrani, S.; Aldossari, K.; Al-Zahrani, J.; Gabr, A. H.; Henkel, Ralf; Ahmad, G. (Wiley, 2017)Reference values of WHO 1999 manual were used for the interpretation of semen analysis until 2010 when new reference values were introduced which have lower cut-off compared to WHO 1999. Therefore, several men who previously ... -
Is there plagiarism in the most influential publications in the field of andrology?
Baskaran, Saradha; Henkel, Ralf; Leisegang, Kristian (Wiley, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Is there plagiarism in the most influential publications in the field of andrology?
Henkel, Ralf (Wiley Online Library, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Microtubular dysfunction and male infertility
Gunes, Sezgin; Sengupta, Pallav; Henkel, Ralf; Alguraigari, Aabed; Sinigaglia, Mariana Marques; Kayal, Malik; Joumah, Ahmad; Agarwal, Ashok (Korean Society for Sexual Medicine and Andrology, 2018)Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain ... -
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
Chung, Eric; Arafa, Mohamed; Henkel, Ralf (Shanghai Institute Materia Medica, 2021)Semen analysis (SA) remains the cornerstone of male infertility evaluation and should ideally be performed by an accredited andrology laboratory or in vitro fertilization (IVF) clinics based on the standards defined ... -
Novel additive for sperm cryopreservation media: Holotheria parva coelomic cavity extract protects human spermatozoa against oxidative stress—A pilot study
Henkel, Ralf; Khashavi, Zahra; Homaei, Ahmad (Wiley-Blackwell, 2020)Cryopreservation is the most effective method for preserving semen for a long period of time. However, during the freeze–thaw process, production of reactive oxygen species (ROS) leads to a steep reduction in sperm fertility ... -
Oxidative stress and assisted reproduction: A comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment
Agarwal, Ashok; Rosas, Israel Maldonado; Henkel, Ralf (MDPI, 2022)Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and antioxidants has been established as an important factor that can negatively affect the outcomes of assisted reproductive techniques ... -
Oxidative stress: A comprehensive review of biochemical, molecular, and genetic aspects in the pathogenesis and management of varicocele
Henkel, Ralf; Agarwal, Ashok; Sharma, Rakesh K; Gupta, Sajal (Korean Society for Sexual Medicine and Andrology, 2021)Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its primary edition, 40 years ago. ... -
PICSI vs. MACS for abnormal sperm DNA fragmentation ICSI cases: A prospective randomized trial
Henkel, Ralf; Hasanen, Eman; Elqusi, Khaled (Springer Nature, 2020)Purpose: To know which sperm selection technique, physiological intracytoplasmic sperm injection (PICSI) or magnetic-activated cell sorting (MACS), is better for the selection of sperm with abnormal sperm DNA fragmentation ... -
Quest for the best—a move to anatomical endoscopic enucleation of the prostate
Henkel, Ralf; Cho, Chaklam; Teoh, Jeremy Yuen Chun (Wiley-Blackwell, 2020)The history of surgical enucleation for the treatment of lower urinary tract symptoms caused by benign prostatic enlargement dates back more than 100 years (Freyer, 1919). Open prostatec-tomy (OP) is an invasive procedure ... -
Radiations and male fertility
Kesari, Kavindra Kumar; Agarwal, Ashok; Henkel, Ralf (Springer Nature, 2018)During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat ... -
Reactive oxygen species and male reproductive hormones
Darbandi, Mahsa; Darbandi, Sara; Agarwal, Ashok; Sengupta, Pallav; Durairajanayagam, Damayanthi; Henkel, Ralf; Sadeghi, Mohammad Reza (BMC, 2018)Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ... -
Reactive oxygen species and male reproductive hormones
Darbandi, Mahsa; Darbandi, Sara; Agarwal, Ashok; Sengupta, Pallav; Durairajanayagam, Damayanthi; Henkel, Ralf; Sadeghi, Mohammad Reza (BMC, 2018)Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ...