Browsing Research Articles (Medical Bioscience) by Title
Now showing items 205-224 of 256
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Reconstruction of major maternal and paternal lineages of the Cape Muslim population
(Sociedade Brasileira de Genética, 2013)The earliest Cape Muslims were brought to the Cape (Cape Town - South Africa) from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they ... -
Records of ctenophores from South Africa
(PeerJ Inc., 2021)Although ctenophores can be conspicuous components of the plankton in coastal marine ecosystems, only six species have been formally described from around South Africa. Using photographs from local community scientists, ... -
Regulation of AKT/AMPK signaling, autophagy and mitigation of apoptosis in Rutin-pretreated SH-SY5Y cells exposed to MPP+
(Springer Nature, 2021)Accumulating evidence suggest that apoptosis, autophagy and dysregulation of signaling pathways are common mechanisms involved in Parkinson’s disease (PD) pathogenesis, and thus development of therapeutic agents targeting ... -
The relationship between seminal leukocytes, oxidative status in the ejaculate, and apoptotic markers in human spermatozoa
(Taylor & Francis, 2013)The aim of this study was to investigate the relationship between seminal leukocytes, reactive oxygen species (ROS) production in the ejaculate, and markers of apoptosis in human spermatozoa. Semen samples were collected ... -
Relative contribution of various chronic diseases and multi-morbidity to potential disability among Dutch elderly
(2018, 2018)BACKGROUND: The amount of time spent living with disease greatly influences elderly people’s wellbeing, disability and healthcare costs, but differs by disease, age and sex. METHODS: We assessed how various single and ... -
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive leukocytes at a concentration >1×106 /mL of semen. Granular leukocytes when activated are capable of ... -
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive leukocytes at a concentration >1×106 /mL of semen. Granular leukocytes when activated are capable of ... -
Reply to Pallotti et al. comment on “Boitrelle et al. The sixth edition of the who manual for human semen analysis: A critical review and swot analysis. Life 2021, 11, 1368"
(MDPI, 2022)We would like to thank F. Pallotti and his colleagues for their positive comments [1] on our SWOT analysis of the strengths, weaknesses, threats and opportunities of the sixth edition of the WHO manual on semen analysis ... -
Response to letter to the Editor: The therapeutic strategy of drug re-positioning to induce autophagic cell death in brain malignancy
(Springer Nature, 2021)We thank Dr Yoshida for his valuable comments and interest in our study which describes the anti-cancer activity of DS00329, a novel derivative of the anti-psychotic drug phenothiazine, in glioblastoma multiforme (GBM) ... -
Risk factors of preterm delivery of low birth weight (plbw) in an African population
(Academic Journals, 2010)More than 20 million infants in the world (15.5% of all births) are born with low birth weight. Ninety-five percent of them are in developing countries. The objective of this study was to examine different factors which ... -
Risk factors of preterm delivery of low birth weight (plbw) in an African population
(Academic Journals, 2010)More than 20 million infants in the world (15.5% of all births) are born with low birth weight. Ninety-five percent of them are in developing countries. The objective of this study was to examine different factors which ... -
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ... -
Role of cytocentrifugation combined with nuclear fast picroindigocarmine staining in detecting cryptozoospermia in men diagnosed with azoospermia
(Seoul: Korean Society for Sexual Medicine and Andrology, 2022)Azoospermia is defined as the absence of spermatozoa in the pellet of a centrifuged semen sample. In fact, when a basic semen analysis fails to detect sperm in the ejaculate, there is still the possibility of detecting ... -
The role of infections and leukocytes in male infertility
(Blackwell Publishing Ltd, 2021)Declining birth rates are one of the problems facing society today. Male counterparts are responsible for about half of the infertility cases, and genitourinary tract infections may play a contributing role in approximately ... -
The role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis
(MDPI, 2012)A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The subsequent efficient human-to-human transmission of ... -
Rutin as a potent antioxidant: implications for neurodegenerative disorders
(Hindawi Publishing Corporation, 2018)A wide range of neurodegenerative diseases (NDs), including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and prion diseases, share common mechanisms such as neuronal loss, apoptosis, mitochondrial ... -
Scientific landscape of oxidative stress in male reproductive research: A scientometric study
(Elsevier, 2020)Unraveling the role of reactive oxygen species and associated oxidative stress (OS) in male reproduction is one of the key areas of male reproductive research. This article illustrates the scientific landscape of OS in ... -
The scientific merit of Carpobrotus mellei L. based on antimicrobial activity and chemical profiling
(Academic Journals, 2006)Species of the genus Carpobrotus are similar in appearance and have been used for medicinal purposes over many generations. Carpobrotus mellei is endemic to the south-Western Cape of South Africa, and also used for various ... -
A scientometric analysis of research publications on male infertility and assisted reproductive technology
(Blackwell Publishing Ltd, 2021)Assisted reproductive technologies (ART) are considered as one of the primary management options to address severe male factor infertility. The purpose of this study was to identify the research trends in the field of male ... -
Seasonal variation of citrinin in traditionally brewed African beer
(Academic Journals, 2013)A seasonal study on citrinin concentrations in traditional beer was conducted using a standardised enzyme-linked immunosorbent assay. Representative samples of indigenous South African beer were collected during the hot, ...