Browsing Research Articles (Medical Bioscience) by Title
Now showing items 212-231 of 256
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Reply to Pallotti et al. comment on “Boitrelle et al. The sixth edition of the who manual for human semen analysis: A critical review and swot analysis. Life 2021, 11, 1368"
(MDPI, 2022)We would like to thank F. Pallotti and his colleagues for their positive comments [1] on our SWOT analysis of the strengths, weaknesses, threats and opportunities of the sixth edition of the WHO manual on semen analysis ... -
Response to letter to the Editor: The therapeutic strategy of drug re-positioning to induce autophagic cell death in brain malignancy
(Springer Nature, 2021)We thank Dr Yoshida for his valuable comments and interest in our study which describes the anti-cancer activity of DS00329, a novel derivative of the anti-psychotic drug phenothiazine, in glioblastoma multiforme (GBM) ... -
Risk factors of preterm delivery of low birth weight (plbw) in an African population
(Academic Journals, 2010)More than 20 million infants in the world (15.5% of all births) are born with low birth weight. Ninety-five percent of them are in developing countries. The objective of this study was to examine different factors which ... -
Risk factors of preterm delivery of low birth weight (plbw) in an African population
(Academic Journals, 2010)More than 20 million infants in the world (15.5% of all births) are born with low birth weight. Ninety-five percent of them are in developing countries. The objective of this study was to examine different factors which ... -
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ... -
Role of cytocentrifugation combined with nuclear fast picroindigocarmine staining in detecting cryptozoospermia in men diagnosed with azoospermia
(Seoul: Korean Society for Sexual Medicine and Andrology, 2022)Azoospermia is defined as the absence of spermatozoa in the pellet of a centrifuged semen sample. In fact, when a basic semen analysis fails to detect sperm in the ejaculate, there is still the possibility of detecting ... -
The role of infections and leukocytes in male infertility
(Blackwell Publishing Ltd, 2021)Declining birth rates are one of the problems facing society today. Male counterparts are responsible for about half of the infertility cases, and genitourinary tract infections may play a contributing role in approximately ... -
The role of Severe Acute Respiratory Syndrome (SARS)-Coronavirus Accessory Proteins in Virus Pathogenesis
(MDPI, 2012)A respiratory disease caused by a novel coronavirus, termed the severe acute respiratory syndrome coronavirus (SARS-CoV), was first reported in China in late 2002. The subsequent efficient human-to-human transmission of ... -
Rutin as a potent antioxidant: implications for neurodegenerative disorders
(Hindawi Publishing Corporation, 2018)A wide range of neurodegenerative diseases (NDs), including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and prion diseases, share common mechanisms such as neuronal loss, apoptosis, mitochondrial ... -
Scientific landscape of oxidative stress in male reproductive research: A scientometric study
(Elsevier, 2020)Unraveling the role of reactive oxygen species and associated oxidative stress (OS) in male reproduction is one of the key areas of male reproductive research. This article illustrates the scientific landscape of OS in ... -
The scientific merit of Carpobrotus mellei L. based on antimicrobial activity and chemical profiling
(Academic Journals, 2006)Species of the genus Carpobrotus are similar in appearance and have been used for medicinal purposes over many generations. Carpobrotus mellei is endemic to the south-Western Cape of South Africa, and also used for various ... -
A scientometric analysis of research publications on male infertility and assisted reproductive technology
(Blackwell Publishing Ltd, 2021)Assisted reproductive technologies (ART) are considered as one of the primary management options to address severe male factor infertility. The purpose of this study was to identify the research trends in the field of male ... -
Seasonal variation of citrinin in traditionally brewed African beer
(Academic Journals, 2013)A seasonal study on citrinin concentrations in traditional beer was conducted using a standardised enzyme-linked immunosorbent assay. Representative samples of indigenous South African beer were collected during the hot, ... -
Seminal oxidation–reduction potential levels are not influenced by the presence of leucocytospermia
(Wiley-Blackwell, 2020)Oxidative stress (OS) is characterised by an excessive amount of reactive oxygen species (ROS) which negatively affect sperm functions. In this study, the influence of leucocytes on seminal oxidation–reduction potential ... -
Semiquantitative promoter methylation of MLH1 and MSH2 genes and their impact on sperm DNA fragmentation and chromatin condensation in infertile men
(Blackwell Publishing Ltd, 2021)To investigate the semiquantitative methylation alterations of MLH1 and MSH2 and the possible association among methylation of MLH1 and MSH2, sperm DNA fragmentation and sperm chromatin condensation in idiopathic ... -
The Severe Acute Respiratory Syndrome Coronavirus 3a Protein Up-Regulates Expression of Fibrinogen in Lung Epithelial Cells
(American Society for Microbiology, 2005)Here we analyzed the gene expression profile of cells that stably express the severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein to determine its effects on host functions. A lung epithelial cell-line, ... -
Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT
(Elsevier, 2006)Severe acute respiratory syndrome coronavirus (SARS-CoV) 7a is an accessory protein with no known homologues. In this study, we report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing ... -
Silver nanoparticles stimulates spermatogenesis impairments and hematological alterations in testis and epididymis of Male rats
(MDPI, 2020)The potential pharmaceutical application of nanoparticles has led to the toxicity within the male reproductive system. In the present study, the effects of silver nanoparticles (Ag-NPs) on hematological parameters, free ... -
A simple point of care test can indicate the need for periodontal therapy to reduce the risk for adverse pregnancy outcomes in mothers attending antenatal clinics
(Taylor & Francis Group, 2017)INTRODUCTION: Although the association between periodontal disease (PD) and adverse pregnancy outcomes has gained recognition amongst antenatal healthcare workers, not much has changed in practice to address it. This ... -
The sixth edition of the WHO manual for human semen analysis: A critical review and SWOT analysis
(MDPI, 2021)Semen analysis is the cornerstone of male fertility evaluation with WHO guidelines providing the basis for procedural standardization and reference values worldwide. The first WHO manual was published in 1980, and five ...