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In Silico Sperm Proteome Analysis to Investigate DNA Repair Mechanisms in Varicocele Patients
(Frontiers Media S.A., 2021-12-17)
Varicocele, a condition associated with increased oxidative stress, negatively affects sperm DNA integrity and reduces pregnancy rates. However, the molecular mechanisms related to DNA integrity, damage, and repair in ...
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
(Elsevier, 2021)
Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ...
The effect of sperm DNA fragmentation on intracytoplasmic sperm injection outcome
(Wiley, 2021)
Our study objective was to assess the effect of various sperm DNA fragmentation
levels on clinical intracytoplasmic sperm injection outcome. This retrospective study
included 392 patients who underwent ICSI and performed ...
Male infertility, oxidative stress and antioxidants
(IntechOpen, 2021)
Within the male reproductive system, oxidative stress (OS) has been identified
as prevailing etiology of male infertility. The effects of reactive oxygen species
(ROS) on male fertility depend on the dimensions, “modus ...
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)
The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive
leukocytes at a concentration >1×106
/mL of semen. Granular leukocytes when activated are capable of ...
Sperm morphology assessment in the era of intracytoplasmic sperm injection: Reliable results require focus on standardization, quality control, and training
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures
are conducted according to the World Health Organization (WHO) guidelines, semen analysis ...
Semiquantitative promoter methylation of MLH1 and MSH2 genes and their impact on sperm DNA fragmentation and chromatin condensation in infertile men
(Blackwell Publishing Ltd, 2021)
To investigate the semiquantitative methylation alterations of MLH1 and MSH2 and the possible association among methylation of MLH1 and MSH2, sperm DNA fragmentation and sperm chromatin condensation in idiopathic ...
Editorial commentary on draft of world health organization sixth edition laboratory manual for the examination and processing of human semen
(Korean Society for Sexual Medicine and Andrology, 2021)
Semen examination is the cornerstone of the evaluation of male fertility potential. Despite its apparent
simplicity, it is a complex series of assessments with
highly variable results that are subject to interpretation. ...
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
(Shanghai Institute Materia Medica, 2021)
Semen analysis (SA) remains the
cornerstone of male infertility evaluation
and should ideally be performed by an
accredited andrology laboratory or in
vitro fertilization (IVF) clinics based on
the standards defined ...
Relevance of leukocytospermia and semen culture and its true place in diagnosing and treating male infertility
(Korean Society for Sexual Medicine and Andrology, 2021)
The current WHO 2010 manual for human semen analysis defines leukocytospermia as the presence of peroxidase-positive
leukocytes at a concentration >1×106
/mL of semen. Granular leukocytes when activated are capable of ...