Faculty of Natural Sciences: Recent submissions
Now showing items 1541-1560 of 2642
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Intact HIV proviruses persist in children seven to nine years after initiation of antiretroviral therapy in the first year of life
(American Society for Microbiology, 2020)In adults starting antiretroviral therapy (ART) during acute infection, 2% of proviruses that persist on ART are genetically intact by sequence analysis. In contrast, a recent report in children treated early failed to ... -
Using sap flow data to assess variations in water use and water status of apple orchards of varying age groups in the western cape province of South Africa
(Water Research Commission, 2020)No accurate quantitative information currently exists on how water use of apple (Malus domestica) orchards varies from planting to full-bearing age, leading to poor irrigation and water allocation decision making. This ... -
Functional and structural analysis of predicted proteins obtained from homo sapiens' minisatellite 33.15-tagged transcript pAKT-45 variants
(Hindawi, 2020)The spermatozoa are transcriptionally dormant entities which have been recognized to be an archive of mRNA, coding for a variety of functionally crucial cellular proteins. This significant repository of mRNA is predicted ... -
Sleep deprivation and neurological disorders
(Hindawi, 2020)Sleep plays an important role in maintaining neuronal circuitry, signalling and helps maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian physiology and exerts a negative impact on brain ... -
Water distribution network leak detection management
(Curran Associates Inc., 2020)Water is becoming an increasingly scarce commodity and must be effectively managed to ensure minimal losses. Water is a basic human resource and during both a physical and a cyber war, limiting, or interrupting the supply ... -
An ontology for the south african protection of personal information act
(Curran Associates Inc., 2020)The protection and management of data, and especially personal information, is becoming an issue of critical importance in both the business environment and in general society. Various institutions have justifiable reasons ... -
Regional rainfall prediction using support vector machine classification of large-scale precipitation maps
(Institute of Electrical and Electronics Engineers Inc., 2020)Rainfall prediction helps planners anticipate potential social and economic impacts produced by too much or too little rain. This research investigates a class-based approach to rainfall prediction from 1-30 days in advance. ... -
Photo-assisted bio-fabrication of silver nanoparticles using Annona muricata leaf extract: exploring the antioxidant, anti-diabetic, antimicrobial, and cytotoxic activities
(Elsevier, 2020)Green synthesis of metal nanoparticles is reputed to have a robust range of biomedical applications. Silver nanoparticles (AgNPs) bio-fabricated using aqueous leaf extract of Annona muricata were characterized and evaluated ... -
South Africa: Challenges and successes of the COVID-19 lockdown
(Elsevier, 2020)At the beginning of March 2020, South Africa (59 million inhabitants) was hit by the pandemic of COVID-19 and soon became the most affected country in Africa by the SARS-CoV-2 virus. From one single case on March 5th, the ... -
The beneficial role of anchomanes difformis in stz-induced reproductive dysfunction in male wistar rats
(Dove Medical Press, 2020)Progression of diabetes mellitus has increasingly led to several diabetic complications. Diabetes is one of the major factors implicated in male reproductive system damage. Recent approaches such as the use of medicinal ... -
HIV-1 diversity and the implementation of integrase strand-transfer inhibitors as part of combination antiretroviral therapy
(SAMA, 2020): The integrase (IN) strand-transfer inhibitor (InSTI) dolutegravir (DTG) is now recommended by the World Health Organization as part of salvage and/or first-line combination antiretroviral therapy (cART).[1] DTG has a ... -
Socio-demographic and modifiable risk factors of diabetes and hypertension among resource constrained patients from rural areas in mdantsane township in South Africa
(Makerere University, 2020)Recently, developing countries have shown a dramatic increase in non-communicable diseases (NCDs). The burden of NCDs in South Africa has increased over the past years resulting in an estimated 37% of all-cause mortality ... -
Understanding the epidemiology, pathophysiology, diagnosis and management of SARS-CoV-2
(SAGE, 2020)The emergence of coronavirus disease 2019 (COVID-19) in December 2019 has resulted in over 20 million cases and 741,808 deaths globally, affecting more than 200 countries. COVID-19 was declared a pandemic on 11 March 2020 ... -
Establishing a pharmacist–prescriber partnership in publicly funded primary healthcare clinics to optimisantibiotic prescribing in the Western Cape: An exploratory study
(Taylor & Francis, 2020)Promoting evidence-based antibiotic prescribing through successful antimicrobial stewardship (AMS) programmes is critical to preserving the effectiveness of antibiotics for common infections in primary care. This requires ... -
Antibacterial activity of rationally designed antimicrobial peptides.
(Hindawi, 2020)Many infectious diseases are still prevalent in the world’s populations since no effective treatments are available to eradicate them. e reasons may either be the antibiotic resistance towards the available therapeutic ... -
Aqueous leaf extract of Sutherlandia frutescens attenuates ROS-induced apoptosis and loss of mitochondrial membrane potential in MPP+-treated SH-SY5Y cells
(University of Benin, 2020)To investigate the neuroprotective activity of the aqueous extract of Sutherlandia frutescens (SF) against 1-methyl-4-phenylpyridinium (MPP+)-induced toxicity in SH-SY5Y neuroblastoma cells. Methods: SH-SY5Y neuroblastoma ... -
Careful governance of African biobanks
(Elsevier, 2020)The Sydney Statement is one of the first framing documents on the principles for guiding global health security. Framing matters because the funding pool for development assistance for health is finite and has plateaued ... -
Ritalinic acid stimulates human sperm motility and maintains vitality in vitro
(Korean Society for Sexual Medicine and Andrology, 2020)To evaluate the in vitro impact of ritalinic acid (RA), a major metabolite of methylphenidate (drug to treat attention-deficit hyperactivity disorder), on sperm motility, vitality and oxidative stress. Materials and Methods: ... -
A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa
(Makerere University, 2020)Greater access and prolonged exposure to ART may inevitably lead to more treatment failure and increase the need for third-line ART (TLART) in a resource-limited setting. Objective: To describe characteristics and resistance ... -
Pre-race screening and stratification predicts adverse events—A 4-year study in 29585 ultra-marathon entrants, SAFER X
(Wiley-Blackwell, 2020)Pre-race screening and risk stratification in recreational endurance runners may predict adverse events (AEs) during a race. Aim: To determine if pre-race screening and risk stratification predict AEs during a race. Methods: ...