Faculty of Natural Sciences: Recent submissions
Now showing items 1621-1640 of 2642
-
Applications of computational methods in biomedical Breast cancer imaging diagnostics: A review
(MDPI, 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
4-Oxatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione derivatives as NMDA receptor- and VGCC blockers with neuroprotective potential
(MDPI, 2020)The impact of excitotoxicity mediated by N-methyl-D-aspartate (NMDA) receptor overactivation and voltage gated calcium channel (VGCC) depolarization is prominent among the postulated processes involved in the development ... -
Anticorrosion coated stainless steel as durable support for C-N-TiO2 photo catalyst layer
(MDPI, 2020)The development of durable photocatalytic supports resistant in harsh environment has become challenging in advanced oxidation processes (AOPs) focusing on water and wastewater remediation. In this study, stainless steel ... -
Dietary effects of antimicrobial peptides in therapeutics
(Taylor & Francis, 2020-02-17)The notable increase in drug-resistant infections and the failure of the most potent antibiotics to establish their curative effect without side effect have presented a serious need for the discovery of new therapeutic ... -
Synthesis of biogenic gold nanoparticles from terminalia mantaly extracts and the evaluation of their in vitro cytotoxic effects in cancer cells
(MDPI, 202-09-12)Scientists have demonstrated the potential of plant materials as 'green' reducing and stabilizing agents for the synthesis of gold nanoparticles (AuNPs) and opened new ecofriendly horizons to develop effective and less ... -
Effect of calcination time on the physicochemical properties and photocatalytic performance of carbon and nitrogen co-doped TiO2 nanoparticles
(MDPI, 2020)The application of highly active nano catalysts in advanced oxidation processes (AOPs) improves the production of non-selective hydroxyl radicals and co-oxidants for complete remediation of polluted water. This study ... -
Green method synthesised graphene-silver electrochemical nanobiosensors for ethambutol and pyrazinamide
(MDPI, 2020)A novel nanobiosensor was constructed with graphene oxide (GO) sheets coupled to pear extract-based green-synthesised silver nanoparticles (Ag-NPs) to which cytochrome P450-2D6 (CYP2D6) enzyme was attached. The biosensor ... -
The synthesis of 7,9-dimethoxy-3-propyl-3,4-dihydro-1H-benzo[g]isochromene1,5,10-trione: A potential monomer for the synthesis of the natural product xylindein
(Arkivoc, 2020)A novel synthesis of a 3-propyl-substituted-benzo[g]isochromene quinone, a potential monomer of the natural product xylindein, was accomplished in 9 steps (overall yield of 8.2%) from 2,4- dimethoxybenzaldehyde. Key steps ... -
Influence of quantum dot surface on electrochemical DNA sensing mechanism
(Wiley, 2020)Owing to their high surface‐to‐volume ratio, electrocatalytic activity, biocompatibility and novel electron transport properties, quantum dots (QDs) are highly attractive materials for the ultrasensitive detection of ... -
Materials for hydrogen-based energy storage - past, recent progress and future outlook
(Elsevier, 2020)Globally, the accelerating use of renewable energy sources, enabled by increased efficiencies and reduced costs, and driven by the need to mitigate the effects of climate change, has significantly increased research in ... -
The effects of production system and sex on the sensory quality characteristics of dorperb lamb
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)The effect of production systems on the sensory quality characteristics of Dorper lambs was investigated. Sixty lambs (ewes, rams, castrates) were allocated into two production groups (feedlot or free-range) at weaning ... -
COMBAT-TB-NeoDB: Fostering tuberculosis research through integrative analysis using graph database technologies
(Oxford University Press, 2020)Tuberculosis (TB) is a significant global health threat, with onethird of the population infected with its causative agent Mycobacterium tuberculosis (M.tb). Globally, researchers have been responding with a plethora of ... -
Optimal design of combined two-tank latent and metal hydrides-based thermochemical heat storage systems for high-temperature waste heat recovery
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)The integration of thermal energy storage systems (TES) in waste-heat recovery applications shows great potential for energy efficiency improvement. In this study, a 2D mathematical model is formulated to analyze the ... -
Immunological changes during space travel: A ground-based evaluation of the impact of Neutron Dose Rate on Plasma Cytokine levels in human whole blood cultures
(Frontiers Media S.A., 2020)A better understanding of the combined impact of different space stressors on human health is urgently warranted, considering the upcoming long-duration missions beyond lower Earth orbit. Therefore, a growing number of ... -
Stochastic modeling of a mosquito-borne disease
(Springer Nature, 2020)We present and analyze a stochastic differential equation (SDE) model for the population dynamics of a mosquito-borne infectious disease. We prove the solutions to be almost surely positive and global. We introduce a ... -
Structural and molecular docking analytical studies of the predicted ligand binding sites of cadherin-1 in cancer prognostics
(Dove Medical Press, 2020)Several studies have explored the design of antimicrobial peptides (AMPs) for the development of therapeutic and diagnostic molecules for the treatment and identification of pathogenic diseases as well as cancer. Human ... -
Ellagic acid controls cell proliferation and induces apoptosis in breast cancer cells via inhibition of cyclin-dependent kinase 6
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)Cyclin-Dependent Kinase 6 (CDK6) plays an important role in cancer progression, and thus, it is considered as an attractive drug target in anticancer therapeutics. This study presents an evaluation of dietary phytochemicals, ... -
Potential of resampled multispectral data for detecting desmodium-brachiaria intercropped with maize in a 'push-pull' system
(ProQuest, 2020)Poor crop yields remain one of the main causes of chronic food insecurity in Africa. This is largely caused by insect pests, weeds, unfavourable climatic conditions and degraded soils. Weed and pest control, based on the ... -
Applications of computational methods in biomedical breast cancer imaging diagnostics: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
Causes and consequences of sperm mitochondrial dysfunction
(Wiley-Blackwell, 2020)Mitochondria have multiple functions, including synthesis of adenine triphosphate, production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in ...