Browsing Research Articles (School of Pharmacy) by Title
Now showing items 53-72 of 155
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The domestication of the African union model law on medical products regulation: perceived benefits, enabling factors, and challenges
(Frontiers Media, 2023)Introduction: In 2016, the African Union (AU) Model Law on Medical Products Regulation was endorsed by AU Heads of State and Government. The aims of the legislation include harmonisation of regulatory systems, increasing ... -
The domestication of the African Union model law on medical products regulation: Perceived benefits, enabling factors, and challenges
(Frontiers Media S.A., 2023)Introduction: In 2016, the African Union (AU) Model Law on Medical Products Regulation was endorsed by AU Heads of State and Government. The aims of the legislation include harmonisation of regulatory systems, increasing ... -
"Eat dry beans, split peas, lentils and soya regularly": a food-based dietary guideline
(Medpharm, 2013)The objective of this paper is to review recent scientific evidence to support the food-based dietary guideline (FBDG): “Eat dry beans, split peas, lentils and soya regularly”. In this review, legumes are synonymous with ... -
The effectiveness of using text and pictograms on oral rehydration, dry-mixture sachet labels
(AOSIS, 2021)Medication labels are often the only information available to patients after obtaining medication from a healthcare practitioner. Pictograms are graphic symbols that have shown to increase understanding of medicine use ... -
Effects of aqueous leaf extract of Asystasia gangetica on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats
(BioMed Central Ltd, 2013)Background: Asystasia gangentica (A. gangetica) belongs to the family Acanthaceae. It is used to treat hypertension, rheumatism, asthma, diabetes mellitus, and as an anthelmintic in South Africa, India, Cameroun, Nigeria, ... -
Effects of Leonotis leonurus aqueous extract on the isolated perfused rat heart
(Open Access Science Research Publisher, 2012)The use the aqueous decoction of Leonotis leonurus (L. leonurus) (Ll) R. Br. (Lamiaceae) in the treatment of hypertension (HPT) in traditional medicine is well documented. The effect of the aqueous extract of LI on the ... -
Encapsulation of variabilin in stearic acid solid lipid nanoparticles enhances its anticancer activity in vitro
(MDPI, 2020)The use of natural products as chemotherapeutic agents is well established; however, many of these are associated with undesirable side effects, including high toxicity and instability. Furthermore, the development of drug ... -
Epidemiology and outcomes of Clostridium difficile infection among hospitalised patients: results of a multicentre retrospective study in South Africa
(BMJ Publishing Group, 2018)INTRODUCTION Limited data exist on Clostridium difficile infection (CDI) in low-resource settings and settings with high prevalence of HIV. We aimed to determine baseline CDI patient characteristics and management and ... -
Establishing a pharmacist–prescriber partnership in publicly funded primary healthcare clinics to optimisantibiotic prescribing in the Western Cape: An exploratory study
(Taylor & Francis, 2020)Promoting evidence-based antibiotic prescribing through successful antimicrobial stewardship (AMS) programmes is critical to preserving the effectiveness of antibiotics for common infections in primary care. This requires ... -
Establishing a pharmacist–prescriber partnership in publicly funded primary healthcare clinics to optimise antibiotic prescribing in the Western Cape: An exploratory study
(AOSIS, 2020)Promoting evidence-based antibiotic prescribing through successful antimicrobial stewardship (AMS) programmes is critical to preserving the effectiveness of antibiotics for common infections in primary care. This requires ... -
Establishment of the African Medicines Agency: Progress, challenges and regulatory readiness
(Springer Nature, 2021)Insufcient access to quality, safe, efcacious and afordable medical products in Africa has posed a signifcant challenge to public health for decades. In part, this is attributed to weak or absent policies and regulatory ... -
Evaluating pharmacy students’ knowledge and skills in reproductive, maternal, new-born and child health care at a South African university
(Springer Nature, 2021)Maternal and child mortality is a global concern and one of South Africa’s quadruple burdens of disease. As easily accessible frontline healthcare workers, pharmacists play an important role in the continuum of maternal ... -
Evaluation of Antibacterial Activity of Bryopsis pennata and Chaetomorpha antennina against Multidrug Resistant Morganella morganii and Salmonella species Isolated from Healthy Individuals
(International Journal for Pharmaceutical Research Scholars, 2017)The problem of antibiotic resistance is fast becoming a pandemic which has necessitated the need for new drugs discovery. This study was carried out to screen two green algal species- Bryopsis pennata and Chaetomorpha ... -
Evaluation of Terminalia macroptera (Combretaceae) Guill. & Perr stem bark extract incorporated into an emulgel for the potential management of rheumatoid arthritis
(Scientific African, 2023)Background: Rheumatoid Arthritis (RA) is a chronic disease which causes inflammation and damage to the joint. The goals of treatment are to stop inflammation, relieve symptoms, improve physical function and overall well-being. ... -
Evaluation of the antidiarrhoeal and antidiabetic activities of the leaf aqueous extract of Syzygium cordatum hoscht. ex C.Krauss (Mytraceae) in rodents
(Asian Network for Scientific Information, 2013)Syzygium cordatum Hoscht. ex C.Krauss is widely used by traditional medicine practitioners to treat many ailments including diarrhoea and diabetes. Despite the folklore use, little evidence can be found in literature to ... -
Evaluation of the effects of Olea europaea L. subsp. africana (Mill.) P.S. Green (Oleaceae) leaf methanol extract against castor oil-induced diarrhoea in mice
(Oxford University Press, 2010)Olea europaea L. subsp. africana (Mill.) P.S. Green is widely used in South Africa by traditional medicine practitioners to treat diarrhoea. However, little is known scientifically about this South African species in the ... -
Exploring practising pharmacy graduates’ views on improving the effectiveness of pharmacy education at the University of the Western Cape, South Africa
(HEALTH & MEDICAL PUBLISHING GROUP, 2019)South African health professional education institutions have a mandate to produce graduates who are able to address priority needs of the healthcare system and larger society. However, evidence of the effective use of ... -
Exploring the implications of a needs-based pharmacy education framework modelled on population health: Perspective from a developing country
(MDPI, 2019)Globally, health education reform is directing efforts to strengthen the health system through collaboration between health education and health services. However, collaborative efforts vary between developed and developing ... -
Exploring the utility of a spontaneous adverse drug reaction reporting system in identifying drug–drug interactions between antiretrovirals, antitubercular drugs, and cotrimoxazole: a case/non-case analysis
(Springer Nature, 2020)Background: Drug–drug interactions (DDIs) cause significant morbidity and mortality, especially in patients with HIV with opportunistic infections such as tuberculosis. However, the literature on quantitative signal detection ... -
Fractions of Hoslundia opposita Vahl and hoslundin induced apoptosis in human cancer cells via mitochondrial-dependent reactive oxygen species (ROS) generation
(Elsevier, 2022)ancer remains one of the leading causalities of several morbidity and mortality with negative impact on global economy due to low workforce and management/treatment cost. A number of conventional therapies have been ...