Browsing Research Articles (School of Pharmacy) by Author "Green, Ivan"
Now showing items 1-3 of 3
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Cardiovascular effects of the alkaloid hippadine on the isolated perfused rat heart
Mugabo, Pierre; Obikeze, Kenechukwu; Njagi, Angela; Burger, Andries; Dietrich, Danielle; Green, Ivan (Open Access Science Research Publisher, 2012)Crinum macowanii has been used extensively in traditional medicines for treatment of various illnesses such as oedema and ‘heart disease’. Previous studies of the crude bulb extracts on Langendorff perfused isolated rat ... -
Characterization and Cradiovascular Effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a Diterpenoid Isolated from Leonotis leonurus
Obikezea, Kene C.; McKenzieb, Jean M.; Green, Ivan; Mugabo, Pierre (South African Chemical Institute, 2008)A new diterpenoid, (13S)-9 ,13 -epoxylabda-6 (19),15(14)diol dilactone (1), was isolated from Leonotis leonurus and the structure determined via NMR analysis. The compound causes significant changes in blood pressure of ... -
Inorganic ions in leonotis leonurus extract do not explain changes in isolated Wistar rat heart function
Burger, Andries; Mugabo, Pierre; Henkel, Ralf; Green, Ivan (Open Access Science Research Publisher, 2011)Leonotis leonurus (L. leonurus) R. Br (Lamiaceae) is used by healers in South Africa. The present study was conducted to determine if the L. leonurus effect on isolated rat heart is due to ionic changes in the perfusion fluid.