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Now showing items 71-80 of 90
A retrospective analysis of applications for registration of generic medicines processed by the medicines control authority of Zimbabwe
(Springer, 2023)
Many applications for registration of medicines are rejected because applicants fail to submit or resolve critical
deficiencies in the quality, efficacy, and safety of the medicines. The study aimed to establish approval ...
Challenges faced by African healthcare workers during the third wave of the pandemic
(Wiley, 2022)
Africa experienced the third wave of the coronavirus disease in 2019, which caused
an 18% rise in cases in most parts of the continent. As of January 2022, the region
had an estimated 10.4 million cumulative cases and ...
Common Deficiencies Found in the Active Pharmaceutical Ingredient (API) Section of Non-sterile Generic Products Submitted for Registration by SAHPRA
(Springer Science and Business Media Deutschland GmbH, 2023)
Purpose: This research study aims to determine the qualitative and quantitative common deficiencies included in the API section of dossiers submitted to SAHPRA. The study was conducted retrospectively over a 7-year period ...
Marburg virus disease amid Covid-19 in West Africa: An emerging and re-emerging zoonotic epidemic threat, future implications and way forward
(2023)
Amid the coronavirus 2019 (COVID-19) pandemic,
several African countries including Ghana
and Equatorial Guinea have reported several
zoonotic outbreaks. The COVID-19 pandemic
has added more strain on the already ...
Regulatory registration timelines of generic medicines in South Africa: Assessment of the performance of SAHPRA between 2011 and 2022
(Springer, 2023)
Various regulatory authorities are experiencing backlogs of applications which result in delayed access
to medicines for patients. The objective of this study is to critically assess the registration process utilised by ...
Zinc(ii) complex of (z)-4-((4-nitrophenyl)amino)pent-3-en-2-one, a potential antimicrobial agent: Synthesis, characterization, antimicrobial screening, dft calculation and docking study
(Chemical Society of Ethiopia, 2023)
Herein, the synthesis and characterizations of (Z)-4-((4-nitrophenyl)amino)pent-3-en-2-one (HL) ligand and its Zn(II) complex are reported. The compounds were characterized using elemental and thermogravimetric (TGA) ...
Treating urinary tract infections in public sector primary healthcare facilities in Cape Town, South Africa: A pharmaceutical perspective
(South African Medical Association, 2022)
Antibiotic resistance is a global healthcare burden complicating the management of infections. Urinary tract infections (UTIs) are commonly treated in primary care. Managing UTIs appropriately in primary care can combat ...
Situation analysis on the regulation of nanomedicines in Southern Africa
(Frontiers Media, 2023)
Medical products incorporating nanoparticle drug delivery
systems (nanomedicines) are therapeutic or imaging agents, which comprise
a delivery system within the nanometer size range (1 – 1000 nm). As medical
products, ...
The validation of a simple, robust, stability-indicating rp-hplc method for the simultaneous detection of lamivudine, tenofovir disoproxil fumarate, and dolutegravir sodium in bulk material and pharmaceutical formulations
(Hindawi, 2022)
An effective analytical method is requisite to ensure the accurate identification and quantification of drug(s), either in bulk
material or in complex matrices, which form part of finished pharmaceutical products. For the ...
The design and evaluation of ciprofloxacin-loaded nanoformulations using Ipomoea batatas starch nanoparticles
(SpringerOpen, 2023)
Starch nanoparticle derivatives are gaining popularity as drug delivery vehicles because of their biocompatibility,
better mechanical characteristics, heat stability properties, impediment qualities, permeability ...