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SASOCP position statement on the pharmacist’s role in antibiotic stewardship 2018
(AOSIS Publishing, 2018)
Antibiotics are the most commonly prescribed medicines in global healthcare practice today. Their effectiveness is crucial and often life-saving in humanity’s battle against pathogens and infectious diseases. Antibiotic/ ...
Clostridium difficile infection perceptions and practices: a multicenter qualitative study in South Africa
(BMC, 2018)
BACKGROUND: Clostridium difficile infection (CDI) is understudied in limited resource settings. In addition, provider
awareness of CDI as a prevalent threat is unknown. An assessment of current facilitators and barriers ...
Multi-targeted directed ligands for Alzheimer’s disease: design of novel lead coumarin conjugates
(Taylor & Francis, 2018)
Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by central nervous system insults with progressive cognitive (memory, attention) and non-cognitive (anxiety, depression) impairments. Pathophysiological ...
Small molecule efflux pump inhibitors in Mycobacterium tuberculosis: a rational drug design perspective
(Bentham Science Publishers, 2018)
Drug resistance in Mycobacterium tuberculosis (M. tuberculosis) complicates management of tuberculosis. Efflux pumps contribute to low level resistance and acquisition of additional high level resistance mutations through ...
Synthesis and biological evaluations of NO-donating oxa- and aza-pentacycloundecane derivatives as potential neuroprotective candidates
(MDPI, 2018)
In order to utilize the neuroprotective properties of polycyclic cage compounds, and explore
the NO-donating ability of nitrophenyl groups, an array of compounds was synthesized where the
different nitrophenyl groups ...
Allergic rhinitis: To sneeze or to wheeze. Pollen is the question, what is the answer?
(Medpharm Publications, 2018)
Allergic rhinitis, also known colloquially as hay fever, is the most common among the allergic diseases. Recent literature reports that it affects up to a tenth of the world population. Atopic diseases have a particularly ...
A "site" for sore eyes
(South African Academy of Family Physicians, 2018)
It is known that not all red eyes are caused by infections. Furthermore, not all eye infections will react to antibiotic eye drops. Most
cases of conjunctivitis are due to viral causes, do not require antibiotic eye drops ...
Patient with Kaposi’s Sarcoma: Teaching students medicine management therapy
(Medpharm, 2018)
Interprofessional education (IPE) is
a cornerstone in advancing health
professional education, with the aim
of improving the overall quality of
healthcare.1 The World Health Organization
(WHO) states: “Interprofessional ...
An interesting case of carbamazepine-induced Stevens–Johnson Syndrome
(Springer, 2018)
A 29-year-old Black female patient was admitted to a psychiatric ward with symptoms of major depressive disorder with psychosis. The patient was started on amitriptyline 50 mg/day and haloperidol 10 mg/day. On day 4 ...
Medicine Runners: A community-initiated solution to chronic medicine access in underserved communities
(Medpharm, 2018)
Patient access to chronic medicines is crucial in optimising disease management. With the introduction of a decentralised chronic
dispensing unit, stable patients qualify to have access to their chronic medicines away ...