Research Articles (Biotechnology)
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Fungal‑derived compounds and mycogenic nanoparticles with antimycobacterial activity: a review
(Springer, 2022)Tuberculosis (TB) is a persistent lung infection caused by Mycobacterium tuberculosis. The disease is characterized by high mortality rates of over 1 million per year. Unfortunately, the potency and efectiveness of currently ... -
A three-pronged approach to waste composition determination
(Elsevier, 2022-02-01)Understanding solid waste composition has frequently been cited as one of the most valuable resources to those responsible for the proper management of solid waste. The unique contribution of this article lies in the fact ... -
Building HMM and molecular docking analysis for the sensitive detection of anti-viral pneumonia antimicrobial peptides (AMPs)
(Nature Research, 2021)Pneumonia is the main reason for mortality among children under five years, causing 1.6 million deaths every year; late research has exhibited that mortality is increasing in the elderly. A few biomarkers used for its ... -
Green-synthesized zinc oxide nanoparticles mitigate salt stress in sorghum bicolor
(MDPI, 2022)Salinity is an abiotic stress that is responsible for more than 50% of crop losses worldwide. Current strategies to overcome salinity in agriculture are limited to the use of genetically modified crops and chemicals ... -
Methylenetetrahydrofolate Reductase Polymorphism (rs1801133) and the Risk of Hypertension among African Populations: A Narrative Synthesis of Literature
(MDPI, 2022)In this review, we have gathered and analyzed the available genetic evidence on the association between the methylenetetrahydrofolate reductase gene (MTHFR), rs1801133 and the risk of Hypertension (HTN) in African ... -
Morpho-physiological, biochemical, and genetic responses to salinity in medicago truncatula
(MDPI, 2021)We used an integrated morpho-physiological, biochemical, and genetic approach to investigate the salt responses of four lines (TN1.11, TN6.18, JA17, and A10) of Medicago truncatula. Results showed that TN1.11 exhibited a ... -
Gene expression modulation of apoptotic and oestrogen receptor alpha genes by active fractions of selected Nigerian plants on cervical cancer cell line (hela)
(University of Benin, 2021)The roles of natural product in drug discovery and development cannot be over emphasised. It plays a vital role in human therapy and gives a better understanding on the cellular pathways.This study investigated the ... -
Isolation and characterization of lytic proteus virus 309
(MDPI, 2022)Proteus mirabilis is frequently associated with complicated urinary tract infections (UTIs) and is the main cause of catheter-associated urinary tract infections (CAUTIs). Treatment of such infections is complicated and ... -
Effect of copper sulphate and cadmium chloride on non-human primate sperm function in vitro
(MDPI, 2021)Abstract: In order to address the large percentage of unexplained male infertility in humans, more detailed investigations using sperm functional tests are needed to identify possible causes for compromised fertility. Since ... -
Factors associated with glycemic control among South African adult residents of Mkhondo municipality living with diabetes mellitus
(Lippincott, Williams & Wilkins, 2020)This study examines the rate and the influencing factors of glycemic control among adult residents living with DM in Mkhondo Municipality of South Africa. In this cross-sectional study, 157 individuals attending care for ... -
Biological synthesis of gold and silver nanoparticles using leaf extracts of Crassocephalum rubens and their comparative in vitro antioxidant activities
(Elsevier, 2020)The use of plant and plant products in the synthesis of silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) is made possible because of the natural inherent phytochemicals responsible for the reduction of respective ... -
Phenolic content, antioxidant, cytotoxic and antiproliferative effects of fractions of Vigna subterraenea (L.) verdc from Mpumalanga, South Africa
(Elsevier, 2021)Consistent intake of legumes has been correlated with decreased possibility of developing colorectal cancer (CRC) due to the content of some phytochemicals like polyphenols. Bambara groundnut (BGN) is an underutilized ... -
Inhibitory potential of repurposed drugs against the SARS-CoV-2 main protease: A computational-aided approach
(Taylor and Francis, 2020)The exponential increase in cases and mortality of coronavirus disease (COVID-19) has called for a need to develop drugs to treat this infection. Using in silico and molecular docking approaches, this study investigated ... -
Three Novel Bacteria Associated with Two Centric Diatom Species from the Mediterranean Sea, Thalassiosira rotula and Skeletonema marinoi
(MDPI, 2021)Diatoms are a successful group of microalgae at the base of the marine food web. For hundreds of millions of years, they have shared common habitats with bacteria, which favored the onset of interactions at different ... -
Cross-sectional study of the association of 5 single nucleotide polymorphisms with enalapril treatment response among South African adults with hypertension
(NLM (Medline), 2021-11-19)This study investigates the association of 5 single nucleotide polymorphisms (SNPs) in selected genes (ABO, VEGFA, BDKRB2, NOS3, and ADRB2) with blood pressure (BP) response to enalapril. The study further assessed genetic ... -
Multifunctional Gold Nanoparticles for Improved Diagnostic and Therapeutic Applications: A Review
(Springer Open, 2021)The medical properties of metals have been explored for centuries in traditional medicine for the treatment of infections and diseases and still practiced to date. Platinum-based drugs are the first class of metal-based ... -
Isolation and characterization of strain exiguobacterium sp. Krl4, a producer of bioactive secondary metabolites from a Tibetan glacier
(MPDI, 2021)Extremophilic microorganisms represent a unique source of novel natural products. Among them, cold adapted bacteria and particularly alpine microorganisms are still underexplored. Here, we describe the isolation and ... -
Three novel bacteria associated with two centric diatom species from the Mediterranean Sea, Thalassiosira rotula and Skeletonema marinoi
(MPDI, 2021)Diatoms are a successful group of microalgae at the base of the marine food web. For hundreds of millions of years, they have shared common habitats with bacteria, which favored the onset of interactions at different ... -
Assessment of genetic diversity in Tunisian populations of Medicago polymorpha based on SSR markers
(Instituto de Investigaciones Agropecuarias, 2021)Medicago polymorpha L. is a herbaceous legume that can be a useful pasture crop, especially in Mediterranean climates. This study aimed to analyze the genetic variation in five populations of M. polymorpha collected from ... -
Nanotechnology-based strategies for effective and rapid detection of sars-cov-2
(MDPI, 2021)The coronavirus disease 2019 (COVID-19) pandemic has gained worldwide attention and has prompted the development of innovative diagnostics, therapeutics, and vaccines to mitigate the pandemic. Diagnostic methods based ...
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