| dc.description.abstract | Helichrysum Mill. (Asteraceae) is a plant genus comprising distinctively of aromatic plants
of about 500–600 species. Since most of these plants have not been previously studied, extensive
profiling helps to validate their folkloric uses and determine their potential value as sources of plantderived drug candidates. This study, therefore, aims to investigate the antioxidant activity (DPPH,
NO, FRAP); total antioxidant capacity, total phenolic, total flavonoid, and fatty acid compositions
of the aqueous acetone extracts from four Helichrysum plants namely, Helichrysum pandurifolium,
Helichrysum foetidum, Helichrysum petiolare, and Helichrysum cymocum. The results obtained showed
that the H. cymocum extract had the best DPPH radical scavenging activity (IC50 = 11.85 ± 3.20 µg/mL)
and H. petiolare extract had the best nitric oxide scavenging activity (IC50 = 20.81 ± 3.73 µg/mL),
while H. pandurifolium Schrank extract (0.636 ± 0.005 µg/mL) demonstrated the best ferrous reducing
power, all of which are comparable with results from ascorbic acid used as the standard. The IC50
values of the radical scavenging activity ranged from 11.85–41.13 µg/mL (DPPH), 20.81–36.19 µg/mL
(NO), and 0.505–0.636 µg/mL (FRAP), for all the plants studied. The H. petiolare has the highest total
antioxidant capacity (48.50 ± 1.55 mg/g), highest total phenolic content (54.69 ± 0.23 mg/g), and
highest total flavonoid content (56.19 ± 1.01 mg/g) compared with other species. | en_US |
