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K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
(Frontiers, 2019-05-24)
Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ...
Oral health status and treatment needs of pregnant women attending antenatal clinics in KwaZulu-Natal, South Africa
(Hindawi, 2019)
During pregnancy, the oral cavity is characterised by an acidic environment and an inflammatory response brought about by vomiting and changes in hormonal levels, respectively, thereby increasing the mother’s risk of ...
Group B streptococcus serotypes in pregnant women from the Western Cape region of South Africa
(Frontiers, 2018-12-04)
Background: Maternal colonization of Group B streptococci (GBS) during pregnancy is an important risk factor for neonatal morbidity and mortality. The aim of this study was to determine the prevalence and serotype distribution ...
Measuring Streptococcus mutans, Streptococcus sanguinis and Candida albicans biofilm formation using a real-time impedance-based system
(Elsevier, 2019-12-20)
Candida albicans and streptococci are amongst the most common fungal and bacterial organisms present in the
oral cavity, with a growing body of evidence implicating C. albicans in increased caries severity and in ...
Colistin, Carbapenem and Cephalosporin-resistant Klebsiella pneumoniae reported from Misrata, Libya
(Medpharm Publications, 2017)
Background: National surveillance of antimicrobial resistance has become a mandatory approach to control the spread of antimicrobial resistance and for the establishment of antibiotic treatment guidelines. In this study, ...
Candida species carriage in diabetic patients in Misrata, Libya
(Medpharm Publications, 2017)
Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ...
Vitek characterisation of type 2 diabetes-associated Candida species
(Elsevier, 2017)
Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...
A population model for the 2017/18 listeriosis outbreak in South Africa
(PLoS One, 2020-03-12)
We introduce a compartmental model of ordinary differential equations for the population dynamics of listeriosis, and we derive a model for analysing a listeriosis outbreak. The model explicitly accommodates neonatal ...
Biosynthesis, Characterization, and Biological Activities of Procyanidin Capped Silver Nanoparticles
(Multidisciplinary Digital Publishing Institute, 2020-09-19)
In this study, procyanidin dimers and Leucosidea sericea total extract (LSTE) were employed in the synthesis of silver nanoparticles (AgNPs) and characterized by ultraviolet-visible (UV-Visible) spectroscopy, high-resolution ...
Real-time assessment of Candida biofilm formation
(Elsevier, 2021-09)
Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, particularly when the Candida biofilm is composed of drug-resistant species. Although the biofilm formation ...