Medical Bioscience: Recent submissions
Now showing items 141-160 of 277
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Quest for the best—a move to anatomical endoscopic enucleation of the prostate
(Wiley-Blackwell, 2020)The history of surgical enucleation for the treatment of lower urinary tract symptoms caused by benign prostatic enlargement dates back more than 100 years (Freyer, 1919). Open prostatec-tomy (OP) is an invasive procedure ... -
PICSI vs. MACS for abnormal sperm DNA fragmentation ICSI cases: A prospective randomized trial
(Springer Nature, 2020)Purpose: To know which sperm selection technique, physiological intracytoplasmic sperm injection (PICSI) or magnetic-activated cell sorting (MACS), is better for the selection of sperm with abnormal sperm DNA fragmentation ... -
The synergistic and neuroprotective effects of alcohol–antioxidant treatment on blood–brain barrier endothelial cells
(Wiley-Blackwell, 2020)Background: Alcohol (EtOH) is reported to adversely affect one of the most crucial roles of the blood–brain barrier (BBB), the regulation of its permeability, thereby compromising the stability of the homeostatic environment ... -
Is there a link between the pathogenic human Coronavirus envelope protein and immunopathology? A review of the literature
(Frontiers Media S.A., 2020)Since the severe acute respiratory syndrome (SARS) outbreak in 2003, human coronaviruses (hCoVs) have been identified as causative agents of severe acute respiratory tract infections. Two more hCoV outbreaks have since ... -
Alkaloids: Therapeutic Potential against Human Coronaviruses
(MPDI, 2020)Alkaloids are a class of natural products known to have wide pharmacological activity and have great potential for the development of new drugs to treat a wide array of pathologies. Some alkaloids have antiviral activity ... -
Green tea consumption increases sperm concentration and viability in male rats and is safe for reproductive, liver and kidney health
(Springer Nature, 2020)Green tea is a popularly consumed beverage worldwide and contains polyphenols, whose antioxidant activities could improve sperm parameters and fertility thereof. We investigated the effect of green tea on the male rat ... -
Are claudin-5 tight-junction proteins in the blood-brain barrier porous?
(Wolters Kluwer Health, 2020)The capillaries of the brain are particularly special, as they are not simply conduits for blood, but are primarily responsible to ensure that the neurons function in a strictly regulated homeostatic interstitium. Brain ... -
Ethnopharmacology, therapeutic properties and nutritional potentials of Carpobrotus edulis: A comprehensive review
(MPDI, 2020)Carpobrotus edulis, formerly known as Mesembryanthemum edule L, belongs to the Aizoaceae family of plants. It is a facultative halophytic invasive medicinal and edible succulent plant that is native to South Africa and ... -
Tyrosinase and melanogenesis inhibition by indigenous African plants: A review
(Multidisciplinary Digital Publishing Institute (MDPI), 2020)The indiscriminate use of non-regulated skin lighteners among African populations has raised health concerns due to the negative effects associated with skin lightener toxicity. For this reason, there is a growing interest ... -
Immunological changes during space travel: A ground-based evaluation of the impact of Neutron Dose Rate on Plasma Cytokine levels in human whole blood cultures
(Frontiers Media S.A., 2020)A better understanding of the combined impact of different space stressors on human health is urgently warranted, considering the upcoming long-duration missions beyond lower Earth orbit. Therefore, a growing number of ... -
Causes and consequences of sperm mitochondrial dysfunction
(Wiley-Blackwell, 2020)Mitochondria have multiple functions, including synthesis of adenine triphosphate, production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in ... -
Is there plagiarism in the most influential publications in the field of andrology?
(Wiley, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2020)Oxidative stress is pre‐empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ... -
Reactive oxygen species in male reproduction: A boon or a bane?
(Wiley, 2020)Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ... -
Do lifestyle practices impede male fertility?
(John Wiley & Sons, Inc, 2020)Alongside an increasing prevalence of couple and male infertility, evidence suggests there is a global declining trend in male fertility parameters over the past few decades. This may, at least in part, be explained ... -
Measuring Streptococcus mutans, Streptococcus sanguinis and Candida albicans biofilm formation using a real-time impedance-based system
(Elsevier, 2019-12-20)Candida albicans and streptococci are amongst the most common fungal and bacterial organisms present in the oral cavity, with a growing body of evidence implicating C. albicans in increased caries severity and in ... -
Biosynthesis, Characterization, and Biological Activities of Procyanidin Capped Silver Nanoparticles
(Multidisciplinary Digital Publishing Institute, 2020-09-19)In this study, procyanidin dimers and Leucosidea sericea total extract (LSTE) were employed in the synthesis of silver nanoparticles (AgNPs) and characterized by ultraviolet-visible (UV-Visible) spectroscopy, high-resolution ... -
A population model for the 2017/18 listeriosis outbreak in South Africa
(PLoS One, 2020-03-12)We introduce a compartmental model of ordinary differential equations for the population dynamics of listeriosis, and we derive a model for analysing a listeriosis outbreak. The model explicitly accommodates neonatal ... -
Radiations and male fertility
(Springer Nature, 2018)During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat ... -
Antioxidant and apoptosis-inhibition potential of Carpobrotus edulis in a model of parkinson’s disease
(African Association of Physiological Sciences, 2018)Background: Parkinson’s disease (PD) is a neurological disorder resulting from the progressive loss of dopaminergic neurons. There is currently no known cure for PD, thus the search for complementary and alternative medicines ...