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BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: A preliminary investigation in a South African population
(Elsevier, 2013)
BACKGROUND: We evaluated the role that selected variants in serotonin transporter (5-HTT), dopamine receptor 2 (DRD2) and brain-derived neurotrophic factor (BDNF) genes play in PTSD symptom severity in an at-risk population. ...
Evidence that dicot-infecting mastreviruses are particularly prone to inter-species recombination and have likely been circulating in Australia for longer than in Africa and the Middle East
(Elsevier, 2013)
Viruses of the genus Mastrevirus (family Geminiviridae) are transmitted by leafhoppers and infect either mono- or dicotyledonous plants. Here we have determined the full length sequences of 49 dicot-infecting mastrevirus ...
Associations between human leukocyte antigen class I variants and the Mycobacterium tuberculosis subtypes causing disease
(Oxford University Press, 2013)
BACKGROUND. The development of active tuberculosis disease has been shown to be multifactorial. Interactions between host and bacterial genotype may influence disease outcome, with some studies indicating the adaptation ...
Patient-Control Association Study of the Leucine-Rich Repeat Kinase 2 (LRRK2) Gene in South African Parkinson's Disease Patients
(National Institute of Health, 2013)
The leucine-rich repeat kinase 2 (LRRK2) gene is of interest to Parkinson's disease (PD) as it
has been implicated in both familial and sporadic forms of the disorder.1 PD-susceptibility
alleles in LRRK2 appear to be ...
A designed experiments approach to optimizing MALDI-TOF MS spectrum processing parameters enhances detection of antibiotic resistance in Campylobacter jejuni
(Frontiers Media, 2016)
MALDI-TOF MS has been utilized as a reliable and rapid tool for microbial fingerprinting at the genus and species levels. Recently, there has been keen interest in using MALDI-TOF MS beyond the genus and species levels to ...
Molecular characterization of the 16S rRNA Gene of helicobacter fennelliae isolated from stools and blood cultures from paediatric patients in South Africa
(Hindawi, 2011)
Forty strains of H. fennelliae collected from paediatric blood and stool samples over an 18 year period at a children's hospital in
Cape Town, South Africa, were amplified by PCR of the 16S rRNA. Two distinct genotypes ...
Antimicrobial activities of a novel biflavonoid and other constituents from Rhus natalensis
(Academic Journals, 2013)
Phytochemical studies on Rhus natalensis root bark collected from Kenya led to the isolation and
identification of a new biflavonoid (3-(1-(2,4-dihydroxyphenyl)-3,3-bis(4-hydroxyphenyl)-1-oxopropan-2-
yl)-7-methoxy-4H-ch ...
Long-term eclipse timing of white dwarf binaries: an observational hint of a magnetic mechanism at work
(Oxford University Press, 2016)
We present a long-term programme for timing the eclipses of white dwarfs in close binaries to measure apparent and/or real variations in their orbital periods. Our programme includes 67 close binaries, both detached and ...
Additive antibacterial activity of naringenin and antibiotic combinations against multidrug resistant Staphylococcus aureus
(Academic Journals, 2015)
Methicillin-resistant Staphylococcus aureus has been causing numerous problems in the health care
sector. This is mainly due to its ability to develop resistance to a number of antibiotics used to treat
staphylococcal ...
Multilocus sequence typing methods for the emerging Campylobacter species C. hyointestinalis, C. lanienae, C. sputorum, C. concisus, and C. curvus
(Frontiers Media, 2012)
Multilocus sequence typing (MLST) systems have been reported previously for multiple food - and food animal-associated Campylobacter species (e.g., C. jejuni, C. coli, C. lari, and C. fetus) to both differentiate strains ...