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Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cells
(Elsevier, 2006)
The genome of the severe acute respiratory syndrome coronavirus encodes for eight accessory viral proteins with no known homologues in other
coronaviruses. One of these is the 3b protein, which is encoded by the second ...
Genetic lesions within the 3a gene of SARS-CoV
(BioMed Central, 2005)
A series of frameshift mutations within the 3a gene has been observed in culture-derived severe
acute respiratory syndrome coronavirus (SARS-CoV). We report here that viral RNA from clinical
samples obtained from SARS-CoV ...
A Novel Severe Acute Respiratory Syndrome Coronavirus Protein, U274, is transported to the Cell Surface and undergoes Endocytosis
(American Society for Microbiology, 2004)
The severe acute respiratory syndrome coronavirus (SARS-CoV) genome contains open reading frames
(ORFs) that encode for several genes that are homologous to proteins found in all known coronaviruses. These
are the replicase ...
Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT
(Elsevier, 2006)
Severe acute respiratory syndrome coronavirus (SARS-CoV) 7a is an accessory protein with no known homologues. In this study, we
report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing ...
Overexpression of 7a, a Protein Specifically Encoded by the Severe Acute Respiratory Syndrome Coronavirus, Induces Apoptosis via a Caspase-Dependent Pathway
(American Society for Microbiology, 2004)
Besides genes that are homologous to proteins found in other coronaviruses, the severe acute respiratory
syndrome coronavirus genome also contains nine other potential open reading frames. Previously, we have
characterized ...
Amino acids 1055 to 1192 in the S2 Region of severe acute respiratory syndrome Coronavirus S Protein induce neutralizing antibodies: Implications for the development of vaccines and antiviral agents
(American Society for Microbiology, 2005)
The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) interacts with
cellular receptors to mediate membrane fusion, allowing viral entry into host cells; hence it is recognized as the
primary ...
Characterization of a unique group-specific protein (U122) of the severe acute respiratory syndrome coronavirus
(American Society for Microbiology, 2004)
A novel coronavirus (CoV) has been identified as the etiological agent of severe acute respiratory syndrome
(SARS). The SARS-CoV genome encodes the characteristic essential CoV replication and structural proteins.
Additionally, ...
The Severe Acute Respiratory Syndrome Coronavirus 3a Protein Up-Regulates Expression of Fibrinogen in Lung Epithelial Cells
(American Society for Microbiology, 2005)
Here we analyzed the gene expression profile of cells that stably express the severe acute respiratory
syndrome coronavirus (SARS-CoV) 3a protein to determine its effects on host functions. A lung epithelial
cell-line, ...
Cellular Characterization of SARS Coronavirus Nucleocapsid
(Leibniz Research Centre for Working Environment and Human Factors, 2004)
The Severe and Acute Respiratory Syndrome coronavirus (SARS CoV) is a newly-emerged virus that caused an outbreak of atypical pneumonia in the winter of 2002-2003. Polyclonal antibodies raised against the nucleocapsid (N) ...
Profiles of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers
(American Society for Microbiology, 2004)