Browsing Faculty of Natural Sciences by Subject "Biotechnology"
Now showing items 41-59 of 59
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A label-free gold nanoparticles-based optical aptasensor for the detection of retinol binding protein 4
(MDPI, 2022)Retinol-binding protein 4 (RBP4) has been implicated in insulin resistance in rodents and humans with obesity and T2DM, making it a potential biomarker for the early diagnosis of T2DM. However, diagnostic tools for ... -
Microbiome enrichment from contaminated marine sediments unveils novel bacterial strains for petroleum hydrocarbon and heavy metal bioremediation
(Elsevier, 2023)Petroleum hydrocarbons and heavy metals are some of the most widespread contaminants affecting marine ecosystems, urgently needing effective and sustainable remediation solutions. Microbial-based bioremediation is gaining ... -
Nanotechnology-based strategies for treatment of obesity, cancer and anti-microbial resistance: Highlights of the Department of Science and Innovation/mintek Nanotechnology Innovation centre biolabels research node at the University of the Western Cape
(MDPI, 2022)Nanotechnology has recently received much interest in various fields, including medicine. South Africa (SA) was the first country in Africa to adopt the technology with the aim of enhancing the national bio-economy and ... -
Ozone and nitric oxide induce cGMP-dependent and independent transcription of defence genes in tobacco
(Wiley, 2009)Here, we analyse the temporal signatures of ozone (O3)-induced hydrogen peroxide (H2O2) and nitric oxide (NO) and the role of the second messenger guanosine 3′,5′-cyclic monophosphate (cGMP) in transcriptional changes ... -
Plant antimicrobial peptides (pamps): Features, applications, production, expression and challenges
(MDPI, 2022)The quest for an extraordinary array of defense strategies is imperative to reduce the challenges of microbial attacks on plants and animals. Plant antimicrobial peptides (PAMPs) are a subset of antimicrobial peptides ... -
Post-translational cleavage of recombinantly expressed nitrilase from Rhodococcus rhodochrous J1 yields a stable, active helical form
(Wiley, 2007)Nitrilases convert nitriles to the corresponding carboxylic acids and ammonia. The nitrilase from Rhodococcus rhodochrous J1 is known to be inactive as a dimer but to become active on oligomerization. The recombinant enzyme ... -
Prevalence, patterns and determinants of dyslipidaemia among South African adults with comorbidities
(Nature Research, 2022)The present study assessed the prevalence, patterns and determinants of dyslipidaemia among South African adults with multi-morbidities. In this study, 614 individuals with DM and hypertension were recruited. Dyslipidaemia ... -
Proteomic analysis of grape berry cell cultures reveals that developmentally regulated ripening related processes can be studied using cultured cells
(Public Library of Science, 2011)This work describes a proteomics profiling method, optimized and applied to berry cell suspensions to evaluate organ-specific cultures as a platform to study grape berry ripening. Variations in berry ripening within a ... -
Reports of plant-derived nanoparticles for prostate cancer therapy
(MDPI, 2023)Plants have demonstrated potential in providing various types of phytomedicines with chemopreventive properties that can combat prostate cancer. However, despite their promising in vitro activity, the incorporation of ... -
Response of soybean nodules to exogenously applied caffeic acid during NaCl-induced salinity
(Elsevier, 2015)affeic acid acts as an antioxidant to scavenge reactive oxygen species, but its influence on plant responses to abi- otic stresses is only partially understood. Here, we investigated the influence of exogenously applied ... -
A simple, high-throughput modeling approach reveals insights into the mechanism of gametophytic self-incompatibility
(Nature Research, 2016)Specificity in the GSI response results from the S-haplotype-specific molecular interaction of S-locus F-box (SLF/SFB) and SRNase proteins in the self-incompatibility locus (S-locus). The answer to the question of how ... -
Structure and biosynthesis of carotenoids produced by a novel Planococcus sp. isolated from South Africa
(BMC, 2022)The genus Planococcus is comprised of halophilic bacteria generally reported for the production of carotenoid pigments and biosurfactants. In previous work, we showed that the culturing of the orange-pigmented Planococcus ... -
Sustainable agriculture through the enhancement of microbial biocontrol agents: Current challenges and new perspectives
(MDPI, 2023)The future of pesticide usage in agriculture is uncertain due to its unsustainability, adverse environmental impacts, and its association in enhanced phytopathogen resistance. Hence, this situation urges the development ... -
Synthesis, computational and biological studies of alkyltin(IV) N-methyl-N-hydroxyethyl dithiocarbamate complexes
(Elsevier, 2021)Methyltin(IV) of butyltin(IV)–N-hydroxyethyl dithiocarbamate complexes, represented as [(CH3)2Sn(L(OH))2] and [(C4H9)2Sn(L(OH))2] respectively were synthesized and characterized using spectroscopic techniques (1 H, 13C ... -
Synthesis, theoretical calculation, and biological studies of mono- and diphenyltin(iv) complexes of n-methyl-n-hydroxyethyldithiocarbamate
(MDPI, 2022)In this study, chlorophenyltin(IV) [(C6H5)(Cl)Sn(L)2] and diphenyltin(IV) [(C6H5)2Sn(L)2] of N-methyl-N-hydroxyethyldithiocarbamate were prepared and characterized using various spectroscopic methods (FTIR, 1H, 13C, and ... -
Unique aliphatic amidase from a psychrotrophic and haloalkaliphilic nesterenkonia isolate
(American Society for Microbiology, 2011)Nesterenkonia strain AN1 was isolated from a screening program for nitrile- and amide-hydrolyzing microorganisms in Antarctic desert soil samples. Strain AN1 showed significant 16S rRNA sequence identity to known members ... -
Water deficit-induced changes in phenolic acid content in maize leaves is associated with altered expression of cinnamate 4-hydroxylase and p-coumaric acid 3-hydroxylase
(MDPI, 2023)The amino acid phenylalanine is a precursor to phenolic acids that constitute the lignin biosynthetic pathway. Although there is evidence of a role of some phenolic acids in plant responses to pathogens and salinity, ... -
Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations
(Frontiers Media, 2023)Since the first report of outbreaks of African swine fever (ASF) in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia, spreading rapidly via contact with infected animals including domestic pigs and ... -
Whole-genome sequencing of African swine fever virus from wild boars in the Kaliningrad region reveals unique and distinguishing genomic mutations
(Frontiers Media, 2023)Since the first report of outbreaks of African swine fever (ASF) in Georgia in 2007, the disease has expanded into Europe, Russia, and Asia, spreading rapidly via contact with infected animals including domestic pigs and ...