Browsing Faculty of Natural Sciences by Subject "Biotechnology"
Now showing items 1-20 of 59
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Abolishment of morphology‑based taxa and change to binomial species names: 2022 taxonomy update of the ICTV bacterial viruses subcommittee
(Springer, 2023)This article summarises the activities of the Bacterial Viruses Subcommittee of the International Committee on Taxonomy of Viruses for the period of March 2021−March 2022. We provide an overview of the new taxa proposed ... -
Analysis of the differentially expressed proteins and metabolic pathways of honeybush (cyclopia subternata) in response to water deficit stress
(MDPI, 2023)Honeybush (Cyclopia spp.) is a rich source of antioxidant properties and phenolic compounds. Water availability plays a crucial role in plant metabolic processes, and it contributes to overall quality. Thus, this study ... -
Anticancer and drug-sensitizing activities of gold nanoparticles synthesized from cyclopia genistoides (honeybush) extracts
(MDPI, 2023)Synthesis of gold nanoparticles (AuNPs) using phytochemicals has become tremendously prominent in biomedical applications because of its enhanced bioactivity and biocompatibility. In this study, water extracts from the ... -
The antioxidant and in vitro wound healing activity of cotyledon orbiculata aqueous extract and the synthesized biogenic silver nanoparticles
(MDPI, 2022)The synthesis of silver nanoparticles using biogenic methods, particularly plants, has led to the discovery of several effective nanoparticles. In many instances, plant-derived silver nanoparticles have been shown to ... -
The arabidopsis wall associated kinase-like 10 gene encodes a functional guanylyl cyclase and is coexpressed with pathogen defense related genes
(Public Library of Science, 2010)Second messengers have a key role in linking environmental stimuli to physiological responses. One such messenger, guanosine 3′,5′-cyclic monophosphate (cGMP), has long been known to be an essential signaling molecule in ... -
Assessment of genetic diversity in Tunisian populations of Medicago polymorpha based on SSR markers
(Instituto de Investigaciones Agropecuarias, 2021)Medicago polymorpha L. is a herbaceous legume that can be a useful pasture crop, especially in Mediterranean climates. This study aimed to analyze the genetic variation in five populations of M. polymorpha collected from ... -
The association of mthfr (rs1801133) with hypertension in an indigenous South African population
(Frontiers Media, 2022)The current study sought to investigate the association between the methylenetetrahydrofolate reductase (MTHFR) variant (rs1801133) and the risk of developing hypertension (HTN) in an indigenous South African population.A ... -
Bacterial viruses subcommittee and archaeal viruses subcommittee of the ictv: Update of taxonomy changes in 2021
(Springer, 2021)In this article, we – the Bacterial Viruses Subcommittee and the Archaeal Viruses Subcommittee of the International Committee on Taxonomy of Viruses (ICTV) – summarise the results of our activities for the period March ... -
Characterization and expression analysis of heme oxygenase genes from sorghum bicolor
(SAGE Publications, 2019)Heme oxygenases (HOs) have a major role in phytochrome chromophore biosynthesis, and chromophores in turn have antioxidant properties. Plant heme oxygenases are divided into the HO1 sub-family comprising HO1, HO3, and ... -
Comparative proteomics analysis between maize and sorghum uncovers important proteins and metabolic pathways mediating drought tolerance
(MDPI, 2023)Drought severely affects crop yield and yield stability. Maize and sorghum are major crops in Africa and globally, and both are negatively impacted by drought. However, sorghum has a better ability to withstand drought ... -
Comparative venom toxin analyses of Nigerian viperidae and elapidae snakes
(Elsevier, 2023)Envenoming by snakebite is a serious health problem that maims and kills a large number of people, primarily in rural areas of developing African countries. The first comparative venom proteomic analyses of four snakes ... -
Computational insight of dexamethasone against potential targets of SARS-CoV-2
(Taylor and Francis Group, 2022)The health sector has been on the race to find a potent therapy for coronavirus disease (COVID)-19, a diseases caused by severe acute respiratory syndrome coronavirus (SARS-CoV)-2. Repurposed anti-viral drugs have played ... -
Crispr-based multi-gene integration strategies to create saccharomyces cerevisiae strains for consolidated bioprocessing
(MDPI, 2022)Significant engineering of Saccharomyces cerevisiae is required to enable consolidated bioprocessing (CBP) of lignocellulose to ethanol. Genome modification in S. cerevisiae has been successful partly due to its efficient ... -
Descriptive epidemiology of and response to the high pathogenicity avian influenza (h5n8) epidemic in South African coastal seabirds, 2018
(Wiley, 2023)High pathogenicity avian infuenza (HPAI) clade 2.3.4.4b H5N8 virus was detected in coastal seabirds in late 2017 in South Africa, following a devastating epidemic in the commercial poultry and ostrich industries. By May ... -
The determination of the effect(s) of solute carrier family 22‑member 2 (SLC22A2) haplotype variants on drug binding via molecular dynamic simulation systems
(Nature Research, 2022)Single nucleotide polymorphisms detected in the solute carrier member family-22 has been shown to result in a variable response in the treatment of type 2 diabetes mellitus with Metformin. This study predicted a ... -
Development of infectious transcripts and genome manipulation of black queen-cell virus of honey bees
(Microbiology Society, 2002)The South African isolate of Black queen-cell virus (BQCV), a honey bee virus, was previously found to have an 8550 nucleotide genome excluding the poly(A) tail. Its genome contained two ORFs, a 5«-proximal ORF encoding ... -
Drought and exogenous abscisic acid alter hydrogen peroxide accumulation and diferentially regulate the expression of two maize RD22-like genes
(Nature Research, 2017)Increased biosynthesis of abscisic acid (ABA) occurs in plants in response to water defcit, which is mediated by changes in the levels of reactive oxygen species such as H2O2. Water defcit and ABA induce expression of ... -
Efficient superoxide scavenging and metal immobilization in roots determines the level of tolerance to vanadium stress in two contrasting Brassica napus genotypes
(Elsevier, 2018)Brassica napus also known as Rapeseed is a member of the Brassicaceae family which is mainly cultivated for its oil-rich seeds. Indeed, B. napus is ranked the third-largest source of vegetable oil in the world. Brassica ... -
Enhanced anti-bacterial activity of biogenic silver nanoparticles synthesized from terminalia mantaly extracts
(Dove Press, 2019)The global increase in outbreaks and mortality rates associated with multidrug- resistant (MDR) bacteria is a major health concern and calls for alternative treatments. Natural-derived products have shown potential in ... -
Enzymatic and proteomic exploration into the inhibitory activities of lemongrass and lemon essential oils against Botrytis cinerea (causative pathogen of gray mold)
(Frontiers Media, 2023)Essential oils (EOs) have been demonstrated as efficacious against B. cinerea. However, the underpinning enzymatic and proteomic mechanism for these inhibitory effects is not entirely clear. Thus, this study examined the ...