Browsing Faculty of Natural Sciences by Subject "HIV"
Now showing items 1-20 of 21
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Antibacterial activity of rationally designed antimicrobial peptides
(Hindawi, 2020)Many infectious diseases are still prevalent in the world’s populations since no effective treatments are available to eradicate them. e reasons may either be the antibiotic resistance towards the available therapeutic ... -
Association between socio-economic factors and HIV self-testing knowledge amongst South African women
(AOSIS, 2022)Self-testing for HIV is an effective and alternative method of increasing HIV testing rates and a strategy for reaching populations that are underserved by HIV testing services. Nonetheless, many resource-constrained ... -
BANA-positive plaque samples are associated with oral hygiene practices and not CD4+ T cell counts in HIV-positive patients
(Hindawi Publishing Corporation, 2012)Background. The “red complex” microorganisms, namely, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia are considered as potential pathogens causing HIV-associated periodontal diseases. Moreover, ... -
Challenges of biobanking in South Africa to facilitate indigenous research in an environment burdened with human immunodeficiency virus, tuberculosis, and emerging non-communicable diseases
(Mary Ann Liebert, Inc., 2013)The high burden of infectious diseases and the growing problem of noncommunicable and metabolic disease syndromes in South Africa (SA) forces a more focused research approach to facilitate cutting-edge scientific growth ... -
Conductive composite biosensor system for electrochemical indinavir drug detection
(HINDAWI LTD, 2015)Indinavir is a protease inhibitor antiretroviral (ARV) drug, which forms part of the highly active antiretroviral therapy during the treatment of HIV/AIDS. Indinavir undergoes first-pass metabolism through the cytochrome ... -
Correlates of early sexual debut and its associated STI/HIV risk factors among sexually active youths in Malawi
(SAGE Publications, 2017)This study explores the correlates of early sexual debut and risk factors of sexually transmitted infections (STIs) among the youth in Malawi. Data was obtained from the Malawi Demographic Health Survey 2010. Out of a ... -
Epidemiology and outcomes of Clostridium difficile infection among hospitalised patients: results of a multicentre retrospective study in South Africa
(BMJ Publishing Group, 2018)INTRODUCTION Limited data exist on Clostridium difficile infection (CDI) in low-resource settings and settings with high prevalence of HIV. We aimed to determine baseline CDI patient characteristics and management and ... -
Factors associated with antiretroviral treatment failure among people living with HIV on antiretroviral therapy in resource- poor settings: a systematic review and metaanalysis
(BMC, 2020)Background: Despite the increase in the number of people accessing antiretroviral therapy (ART), there is limited data regarding treatment failure and its related factors among HIV-positive individuals enrolled in HIV care ... -
Health trends, inequalities and opportunities in South Africa’s provinces, 1990–2019: Findings from the Global burden of disease 2019 Study
(BMJ Publishing Group, 2022)Over the last 30 years, South Africa has experienced four ’colliding epidemics’ of HIV and tuberculosis, chronic illness and mental health, injury and violence, and maternal, neonatal, and child mortality, which have ... -
HIV/Candida co-infection in Sub-Saharan African women on ART
(Infectious Diseases Society of Southern Africa, the Sexually Transmitted Diseases Society of Southern and the Public Health Association of South Africa., 2013)INTRODUCTION: Sub-Saharan Africa has 23.5 million cases of HIV and is home to 92% of the world’s HIV-positive pregnant women of whom 24% die of pregnancy related complications. Oral candidiasis is a common condition in ... -
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
(AIMS Press, 2021-09-10)The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients ... -
Is human immunodeficiency virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
(BMC, 2013)The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently be associated ... -
Non-booking for antenatal care and risks for vertical HIV transmission among women in Chitungwiza, Zimbabwe: a cross-sectional study
(BMC Pregnancy and Childbirth, 2022)Background: The success of prevention of mother to child transmission of HIV (PMTCT) programs dependents on pregnant women accessing antenatal care (ANC) services. Failure to access ANC throughout the course of pregnancy ... -
Optimal strategy for controlling the spread of HIV/AIDS disease: A case study of South Africa
(Taylor and Francis Group, 2012)HIV/AIDS disease continues to spread alarmingly despite the huge amounts of resources invested infighting it. There is a need to integrate the series of control measures available to ensure a consistentreduction ... -
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ... -
A retrospective descriptive investigation of adult patients receiving third-line antiretroviral therapy in the North West province, South Africa
(Makerere University, 2020)Greater access and prolonged exposure to ART may inevitably lead to more treatment failure and increase the need for third-line ART (TLART) in a resource-limited setting. Objective: To describe characteristics and resistance ... -
Time trends in Tuberculosis mortality across the BRICS: An age-period-cohort analysis for the GBD 2019
(Elsevier, 2022)There were 549,522 tuberculosis deaths across the BRICS in 2019, accounting for 39.3% of global deaths. Among HIV-negative populations, the age-standardised mortality rate (ASMR) of tuberculosis in BRICS remained far ... -
Trends in HIV risk behaviour of incoming first-year students at a South African university: 2007–2012
(Taylor and Francis Group, 2015)The aim of the research on which this article is based was to understand the behavioural changes of the target student populationover time to ensure that future prevention programmes are more effective in changing behaviour. ... -
Tri-infection: Tuberculosis, HIV, COVID-19 and the already strained South African health system
(Elsevier, 2021)The 30th of May 2021 marks the latest significant national address, where President Cyril Ramaphosa moves the country back into level two lockdown with the hopes of curving the new COVID-19 surge while guarding an improving ... -
The validation of a simple, robust, stability-indicating rp-hplc method for the simultaneous detection of lamivudine, tenofovir disoproxil fumarate, and dolutegravir sodium in bulk material and pharmaceutical formulations
(Hindawi, 2022)An effective analytical method is requisite to ensure the accurate identification and quantification of drug(s), either in bulk material or in complex matrices, which form part of finished pharmaceutical products. For the ...