Browsing Faculty of Natural Sciences by Subject "Male infertility"
Now showing items 1-20 of 43
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Aqueous extractions of mondia whitei root improve human sperm function in vitro
(Elsevier B.V., 2024)Introduction: Mondia whitei (Mw) is a prominent African medicinal plant that is widely used as traditional treatment in the management of sexual dysfunction and male infertility. Yet, there is a paucity of scientific ... -
Aqueous extractions of Mondia whitei root improve human sperm function in vitro
(Elsevier B.V., 2024)Introduction: Mondia whitei (Mw) is a prominent African medicinal plant that is widely used as traditional treatment in the management of sexual dysfunction and male infertility. Yet, there is a paucity of scientific ... -
Causes and consequences of sperm mitochondrial dysfunction
(Wiley-Blackwell, 2020)Mitochondria have multiple functions, including synthesis of adenine triphosphate, production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis. Mitochondria have a significant contribution in ... -
Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentation
(Blackwell Publishing Ltd, 2021)Male infertility has a complex etiology, and many times, the cause is unknown. While routine semen analysis provides an overview of basic semen parameters, such as sperm concentration, motility, viability and morphology, ... -
Controversy and consensus on indications for sperm dna fragmentation testing in male infertility: a global survey, current guidelines, and expert recommendations
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of the World Health Organization laboratory manual for the examination and processing of human semen. Many conditions and risk factors ... -
Determination of seminal oxidation–reduction potential (ORP) as an easy and cost-effective clinical marker of male infertility
(Wiley, 2017)Oxidative stress (OS) is an important contributing factor to male infertility. While previous methods to measure seminal OS are time-consuming and limited to the use of freshly produced semen, oxidation reduction potential ... -
Diagnostic value of advanced semen analysis in evaluation of male infertility
(Blackwell Publishing Ltd, 2021)Conventional semen analysis is the standard of care to initially evaluate the fertility status of a male patient. However, it has some limitations and among these are failure to correctly identify the aetiology underlying ... -
Diagnostic value of routine semen analysis in clinical andrology
(Blackwell Publishing Ltd, 2021)Infertility is a major health issue affecting over 48.5 million couples around the world, with the male factor accounting for about 50% of the cases. The conventional semen analysis recommended by the World Health Organization ... -
Do lifestyle practices impede male fertility?
(John Wiley & Sons, Inc, 2020)Alongside an increasing prevalence of couple and male infertility, evidence suggests there is a global declining trend in male fertility parameters over the past few decades. This may, at least in part, be explained ... -
Environmental contaminants and male infertility: Effects and mechanisms
(Blackwell Publishing Ltd, 2021)The escalating prevalence of male infertility and decreasing trend in sperm quality have been correlated with rapid industrialisation and the associated discharge of an excess of synthetic substances into the environment. ... -
Epididymal contribution to male infertility: An overlooked problem
(Blackwell Publishing Ltd, 2021)The diagnosis and treatment of male infertility, excluding assisted conception, are limited because of, but not limited to, poor understanding of sperm post-testicular development and storage. Many may think that sperm ... -
Etiologies of sperm DNA damage and its impact on male infertility
(Blackwell Publishing Ltd, 2021)Male factor is responsible for up to 50% of infertility cases in the world. Semen analysis is considered the cornerstone of laboratory evaluation of male infertility, but it has its own drawbacks and fails to predict the ... -
Evaluation of reference values of standard semen parameters in fertile Egyptian men
(Wiley, 2018)The reference values of human semen, published in the WHO’s latest edition in 2010, were lower than those previously reported. The objective of this study was to evaluate reference values of standard semen parameters in ... -
Evaluation of seminal oxidation–reduction potential in male infertility
(Blackwell Publishing Ltd, 2021)The role of oxidative stress in male infertility has been broadly recognised, and the search for a new marker to determine the redox environment in semen has gained considerable interest. Oxidation–reduction potential (ORP) ... -
The excessive use of antioxidant therapy: A possible cause of male infertility?
(Wiley, 2018)Reactive oxygen species and oxidative stress are closely associated with various pathologies such as neurodegenerative diseases, ageing and male infertility. Hence, antioxidants such as vitamin C, vitamin E, N‐acetyl ... -
A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility
(The world journal of men's health, 2021)Globally, infertility impacts 15% of couples trying to conceive. The incidence of male infertility has been increasing over the past several decades, ranging from 20% to 70% worldwide [1,2]. The male partner is found to ... -
The impact of mitochondrial impairments on sperm function and male fertility: a systematic revie
(BMC, 2024)Background Besides adenine triphosphate (ATP) production for sustaining motility, the mitochondria of sperm also host other critical cellular functions during germ cell development and fertilization including calcium ... -
The impact of mitochondrial impairments on sperm function and male fertility: a systematic review
(University of the Western Cape, 2024)Background Besides adenine triphosphate (ATP) production for sustaining motility, the mitochondria of sperm also host other critical cellular functions during germ cell development and fertilization including calcium ... -
The impact of sperm DNA damage in assisted conception and beyond: recent advances in diagnosis and treatment
(Elsevier, 2013)Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo quality and pregnancy rates, and higher ... -
Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Despite the significant role of varicocele in the pathogenesis of male infertility, the impact of varicocele repair (VR) on conventional semen parameters remains controversial. Only a few systematic reviews and ...