Browsing Research Articles (School of Pharmacy) by Author "Samsodien, Halima"
Now showing items 1-2 of 2
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FTIR, dissolution and anti-viral activity of nevirapine co-crystals
Samsodien, Halima; Bapoo, Rafik; Doms, T.I.; Harneker, Z.; Louw, A.S.; Scheepers, I.C.; Sonday, A.B.; Geldenhuys, B. (OMICS International, 2017)The study uses Fourier Transform Infrared (FTIR) spectroscopy to identify five Nevirapine (NV) co-crystals, determines the dissolution profile of the co-crystals and the antiviral activity comparative to pure NV. Hot ... -
Mechanochemical synthesis and physicochemical characterization of isoniazid and pyrazinamide co-crystals with Glutaric acid
Ngilirabanga, Jean Baptiste; Aucamp, Marique Elizabeth; Samsodien, Halima (Frontiers Media S.A., 2020)The present work reports two novel pharmaceutical co-crystals; 2:1 isoniazid-glutaric acid (INHGA) and 2:1 pyrazinamide-glutaric acid (PGA). Isoniazid and pyrazinamide are key first-line drugs used for the treatment of ...