Browsing Medical Bioscience by Title
Now showing items 256-275 of 293
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SARS-CoV-2 spike protein diversity at an intra-host level, among SARS-CoV-2 infected individuals in South Africa, 2020 to 2022
(Public Library of Science, 2023)Intra-host diversity studies are used to characterise the mutational heterogeneity of SARSCoV-2 infections in order to understand the impact of virus-host adaptations. This study investigated the frequency and diversity ... -
Scientific landscape of oxidative stress in male reproductive research: A scientometric study
(Elsevier, 2020)Unraveling the role of reactive oxygen species and associated oxidative stress (OS) in male reproduction is one of the key areas of male reproductive research. This article illustrates the scientific landscape of OS in ... -
The scientific merit of Carpobrotus mellei L. based on antimicrobial activity and chemical profiling
(Academic Journals, 2006)Species of the genus Carpobrotus are similar in appearance and have been used for medicinal purposes over many generations. Carpobrotus mellei is endemic to the south-Western Cape of South Africa, and also used for various ... -
A scientometric analysis of research publications on male infertility and assisted reproductive technology
(Blackwell Publishing Ltd, 2021)Assisted reproductive technologies (ART) are considered as one of the primary management options to address severe male factor infertility. The purpose of this study was to identify the research trends in the field of male ... -
Seasonal variation of citrinin in traditionally brewed African beer
(Academic Journals, 2013)A seasonal study on citrinin concentrations in traditional beer was conducted using a standardised enzyme-linked immunosorbent assay. Representative samples of indigenous South African beer were collected during the hot, ... -
Seminal oxidation–reduction potential levels are not influenced by the presence of leucocytospermia
(Wiley-Blackwell, 2020)Oxidative stress (OS) is characterised by an excessive amount of reactive oxygen species (ROS) which negatively affect sperm functions. In this study, the influence of leucocytes on seminal oxidation–reduction potential ... -
Semiquantitative promoter methylation of MLH1 and MSH2 genes and their impact on sperm DNA fragmentation and chromatin condensation in infertile men
(Blackwell Publishing Ltd, 2021)To investigate the semiquantitative methylation alterations of MLH1 and MSH2 and the possible association among methylation of MLH1 and MSH2, sperm DNA fragmentation and sperm chromatin condensation in idiopathic ... -
The Severe Acute Respiratory Syndrome Coronavirus 3a Protein Up-Regulates Expression of Fibrinogen in Lung Epithelial Cells
(American Society for Microbiology, 2005)Here we analyzed the gene expression profile of cells that stably express the severe acute respiratory syndrome coronavirus (SARS-CoV) 3a protein to determine its effects on host functions. A lung epithelial cell-line, ... -
Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT
(Elsevier, 2006)Severe acute respiratory syndrome coronavirus (SARS-CoV) 7a is an accessory protein with no known homologues. In this study, we report the interaction of a SARS-CoV 7a and small glutamine-rich tetratricopeptide repeat-containing ... -
Silver nanoparticles stimulates spermatogenesis impairments and hematological alterations in testis and epididymis of Male rats
(MDPI, 2020)The potential pharmaceutical application of nanoparticles has led to the toxicity within the male reproductive system. In the present study, the effects of silver nanoparticles (Ag-NPs) on hematological parameters, free ... -
A simple point of care test can indicate the need for periodontal therapy to reduce the risk for adverse pregnancy outcomes in mothers attending antenatal clinics
(Taylor & Francis Group, 2017)INTRODUCTION: Although the association between periodontal disease (PD) and adverse pregnancy outcomes has gained recognition amongst antenatal healthcare workers, not much has changed in practice to address it. This ... -
The sixth edition of the WHO manual for human semen analysis: A critical review and SWOT analysis
(MDPI, 2021)Semen analysis is the cornerstone of male fertility evaluation with WHO guidelines providing the basis for procedural standardization and reference values worldwide. The first WHO manual was published in 1980, and five ... -
Sleep deprivation and neurological disorders
(Hindawi, 2020)Sleep plays an important role in maintaining neuronal circuitry, signalling and helps maintain overall health and wellbeing. Sleep deprivation (SD) disturbs the circadian physiology and exerts a negative impact on brain ... -
Smoking‐induced genetic and epigenetic alterations in infertile men
(Wiley, 2018)Male fertility rates have shown a progressive decrease in both developing and industrialised countries in the past 50 years. Clinical and epidemiological studies have demonstrated controversial results about the harmful ... -
Sperm morphology assessment in the era of intracytoplasmic sperm injection: Reliable results require focus on standardization, quality control, and training
(Korean Society for Sexual Medicine and Andrology, 2021)Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines, semen analysis ... -
The stability and anti-angiogenic properties of titanium dioxide nanoparticles (tio2nps) using caco-2 cells
(MDPI, 2022)Titanium dioxide nanoparticles (TiO2NPs) are found in a wide range of products such as sunscreen, paints, toothpaste and cosmetics due to their white pigment and high refractive index. These wide-ranging applications ... -
Strengths and limitations of different Chromogenic Media for the identification of Candida species
(Scientific & Academic Publishing, 2012)The treatment of invasive candidiasis and other Candida infections with the appropriate antifungal agent is assisted by the identification of Candida isolates to the species level. Rapid and accurate methods of differentiation ... -
The synergistic and neuroprotective effects of alcohol–antioxidant treatment on blood–brain barrier endothelial cells
(Wiley-Blackwell, 2020)Background: Alcohol (EtOH) is reported to adversely affect one of the most crucial roles of the blood–brain barrier (BBB), the regulation of its permeability, thereby compromising the stability of the homeostatic environment ... -
The threat of aerobic vaginitis to pregnancy and neonatal morbidity
(Women's Health and Action Research Centre, 2017)Aerobic vaginitis (AV) is an endogenous opportunistic infection brought about by the disruption of the normal vaginal microbiota. Its early diagnosis and treatment during pregnancy may reduce the risk of negative pregnancy ... -
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2021)Oxidative stress is pre-empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...