Browsing Medical Bioscience by Author "Leisegang, Kristian"
Now showing items 1-17 of 17
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Alternative medicine and herbal remedies in the treatment of erectile dysfunction: A systematic review
Leisegang, Kristian; Finelli, Renata (Informa UK Limited, trading as Taylor & Francis Group., 2021)Objectives: To systematically review and discuss the current evidence from placebo-controlled clinical trials that investigated the use of alternative medicines and herbal remedies in the management of erectile dysfunction ... -
A comparison between the anthropological and modern day uses of this indigenous herb
Leisegang, Kristian; Campbell, James; Ma, X; De Beer, Sanien (Conference: SA Medical Research Council 6th Annual Research Conference, 2012)Sceletium tortuosum (Fig. 1) is a scrambling succulent ground cover indigenous to the Western and Eastern Cape. It has probably been used for centuries as a mood-altering drug, especially by the Khoisan hunters and Nama ... -
Do lifestyle practices impede male fertility?
Leisegang, Kristian; Dutta, Sulagna (John Wiley & Sons, Inc, 2020)Alongside an increasing prevalence of couple and male infertility, evidence suggests there is a global declining trend in male fertility parameters over the past few decades. This may, at least in part, be explained ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
Leisegang, Kristian; Almaghrawi, Walid; Henkel, Ralf (Elsevier, 2021)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
The effect of Nigella sativa oil and metformin on male seminal parameters and testosterone in Wistar rats exposed to an obesogenic diet
Leisegang, Kristian; Almaghrawi, Walid; Henkel, Ralf (Elsevier, 2020)Obesity is a significant global health and socio-economic challenge, and considered an important risk factor for poor health outcomes including male reproductive dysfunction and infertility. As excess adiposity causes ... -
Effect of the metabolic syndrome on male reproductive function: a case-controlled pilot study
Leisegang, Kristian; Bouic, Patrick J.D.; Henkel, Ralf (Wiley, 2014)The metabolic syndrome (MetS) is a constellation of various risk factors. This study aimed to investigate the effect of MetS on testosterone and progesterone, and semen parameters, in a case-controlled pilot study. Male ... -
A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility
Leisegang, Kristian (The world journal of men's health, 2021)Globally, infertility impacts 15% of couples trying to conceive. The incidence of male infertility has been increasing over the past several decades, ranging from 20% to 70% worldwide [1,2]. The male partner is found to ... -
The impact of COVID-19 on the male reproductive tract and fertility: A systematic review
Sengupta, Pallav; Leisegang, Kristian; Agarwal, Ashok (Informa UK Limited, trading as Taylor & FrancisGroup., 2021)Objective: The COVID-19 pandemic, caused by the acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), remains an ongoing public health challenge. Although males are affected slightly more than females, the impact of ... -
The impact of Covid-19 vaccines on male semen parameters: A retrospective cohort study
Henkel, Ralf; Leisegang, Kristian; Finelli, Renata (University of the Western Cape, 2023)The emergence of SARS-CoV-2 and the subsequent COVID-19 pandemic necessitated the development of adequate vaccines. Despite vaccines being demonstrated to be safe and effective for preventing severe disease and death, ... -
The impact of male overweight on semen quality and outcome of assisted reproduction
Leisegang, Kristian; Henkel, Ralf (Medknow Publications, 2014)The impact of obesity on male reproductive health remains a contested topic as evidence is inconclusive and inconsistent. Even more debatable is the effect of male obesity in assisted reproduction. In the manuscript, ... -
The Impact of Storage Time and Seasonal Harvesting on Levels of Sutherlandins and Sutherlandiosides in Lessertia frutescens
Leisegang, Kristian; Campbell, J; Weitz, F; Henkel, R.R (Conference: Faculty of Community and Health Sciences 2nd Research Day, 2013)In South Africa, an estimate of 70% of the population frequently uses traditional medicine for their health care needs. The use of Lessertia frutescens (Figure 1,2) by various cultural groups dates back to the earlier ... -
An in-depth bibliometric analysis and current perspective on male infertility research
Baskaran, Saradha; Agarwal, Ashok; Leisegang, Kristian; Peter, Natesan Pushparaj; Selvam, Manesh Kumar Panner; Henkel, Ralf (Korean Society for Sexual Medicine and Andrology, 2019)PURPOSE: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to analyze male infertility research ... -
Is there plagiarism in the most influential publications in the field of andrology?
Baskaran, Saradha; Henkel, Ralf; Leisegang, Kristian (Wiley, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Obesity is associated with increased seminal insulin and leptin alongside reduced fertility parameters in a controlled male cohort
Leisegang, Kristian; Menkveld, Roelof; Bouic, Patrick J.D.; Henkel, Ralf (BioMed Central, 2014)Obesity appears to be associated with male reproductive dysfunction and infertility, although this has been inconsistent and inconclusive. Insulin and leptin are known mediators and modulators of the hypothalamus-pituitary-testes ... -
The Use of Probiotics in the Primary Prevention of Atopic Dermatitis: A Systemic Review of the Literature in Light of the Hygiene Hypothesis
Leisegang, Kristian; Xu, Wang; Carmen, Linde (8th Conference of the Federation of African Immunological Societies, 2012)Atopic dermatitis (eczema) is a type 1 hypersensitivity reaction that is common in infants and young children, with incidence increasing in the Industrialised world. Based on epidemiological evidence, the hygiene hypothesis ... -
Utility of Antioxidants in the Treatment of Male Infertility: Clinical Guidelines Based on a Systematic Review and Analysis of Evidence
Agarwal, Ashok; Leisegang, Kristian (The world journal of men's health, 2021)It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants could have a significant role in the treatment of male infertility. The main objectives ... -
The validity and reliability of computer-aided semen analyzers in performing semen analysis: a systematic review
Leisegang, Kristian; Agarwal, Ashok; Renata, Finelli (Translational Andrology and Urology., 2021)Background: Computer-aided sperm analyzers (CASA) are currently used worldwide for semen analysis. However, there are doubts about their reliability to fully substitute the human operator. Therefore, this study aimed to ...