Browsing Medical Bioscience by Author "Agarwal, Ashok"
Now showing items 1-17 of 17
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Controversy and consensus on indications for sperm dna fragmentation testing in male infertility: a global survey, current guidelines, and expert recommendations
Henkel, Ralf; Agarwal, Ashok; Farkouh, Ala'a (Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of the World Health Organization laboratory manual for the examination and processing of human semen. Many conditions and risk factors ... -
Editorial commentary on draft of world health organization sixth edition laboratory manual for the examination and processing of human semen
Kandil, Hussein; Agarwal, Ashok; Henkel, Ralf (Korean Society for Sexual Medicine and Andrology, 2021)Semen examination is the cornerstone of the evaluation of male fertility potential. Despite its apparent simplicity, it is a complex series of assessments with highly variable results that are subject to interpretation. ... -
The excessive use of antioxidant therapy: A possible cause of male infertility?
Henkel, Ralf; Sandhu, Inderpreet Singh; Agarwal, Ashok (Wiley, 2018)Reactive oxygen species and oxidative stress are closely associated with various pathologies such as neurodegenerative diseases, ageing and male infertility. Hence, antioxidants such as vitamin C, vitamin E, N‐acetyl ... -
The impact of COVID-19 on the male reproductive tract and fertility: A systematic review
Sengupta, Pallav; Leisegang, Kristian; Agarwal, Ashok (Informa UK Limited, trading as Taylor & FrancisGroup., 2021)Objective: The COVID-19 pandemic, caused by the acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), remains an ongoing public health challenge. Although males are affected slightly more than females, the impact of ... -
An in-depth bibliometric analysis and current perspective on male infertility research
Baskaran, Saradha; Agarwal, Ashok; Leisegang, Kristian; Peter, Natesan Pushparaj; Selvam, Manesh Kumar Panner; Henkel, Ralf (Korean Society for Sexual Medicine and Andrology, 2019)PURPOSE: Male infertility is emerging as a major, escalating global health problem that imposes the need to investigate research trends in male infertility. The purpose of this study is to analyze male infertility research ... -
Male infertility, oxidative stress and antioxidants
Zhaku, Vegim; Agarwal, Ashok; Henkel, Ralf (IntechOpen, 2021)Within the male reproductive system, oxidative stress (OS) has been identified as prevailing etiology of male infertility. The effects of reactive oxygen species (ROS) on male fertility depend on the dimensions, “modus ... -
Microtubular dysfunction and male infertility
Gunes, Sezgin; Sengupta, Pallav; Henkel, Ralf; Alguraigari, Aabed; Sinigaglia, Mariana Marques; Kayal, Malik; Joumah, Ahmad; Agarwal, Ashok (Korean Society for Sexual Medicine and Andrology, 2018)Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain ... -
Oxidative stress and assisted reproduction: A comprehensive review of its pathophysiological role and strategies for optimizing embryo culture environment
Agarwal, Ashok; Rosas, Israel Maldonado; Henkel, Ralf (MDPI, 2022)Oxidative stress (OS) due to an imbalance between reactive oxygen species (ROS) and antioxidants has been established as an important factor that can negatively affect the outcomes of assisted reproductive techniques ... -
Oxidative stress: A comprehensive review of biochemical, molecular, and genetic aspects in the pathogenesis and management of varicocele
Henkel, Ralf; Agarwal, Ashok; Sharma, Rakesh K; Gupta, Sajal (Korean Society for Sexual Medicine and Andrology, 2021)Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its primary edition, 40 years ago. ... -
Radiations and male fertility
Kesari, Kavindra Kumar; Agarwal, Ashok; Henkel, Ralf (Springer Nature, 2018)During recent years, an increasing percentage of male infertility has to be attributed to an array of environmental, health and lifestyle factors. Male infertility is likely to be affected by the intense exposure to heat ... -
Reactive oxygen species and male reproductive hormones
Darbandi, Mahsa; Darbandi, Sara; Agarwal, Ashok; Sengupta, Pallav; Durairajanayagam, Damayanthi; Henkel, Ralf; Sadeghi, Mohammad Reza (BMC, 2018)Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ... -
Reactive oxygen species and male reproductive hormones
Darbandi, Mahsa; Darbandi, Sara; Agarwal, Ashok; Sengupta, Pallav; Durairajanayagam, Damayanthi; Henkel, Ralf; Sadeghi, Mohammad Reza (BMC, 2018)Reports of the increasing incidence of male infertility paired with decreasing semen quality have triggered studies on the effects of lifestyle and environmental factors on the male reproductive potential. There are ... -
Scientific landscape of oxidative stress in male reproductive research: A scientometric study
Henkel, Ralf; Agarwal, Ashok; Baskaran, Saradha (Elsevier, 2020)Unraveling the role of reactive oxygen species and associated oxidative stress (OS) in male reproduction is one of the key areas of male reproductive research. This article illustrates the scientific landscape of OS in ... -
Seminal oxidation–reduction potential levels are not influenced by the presence of leucocytospermia
Henkel, Ralf; Arafa, Mohamed Mostafa; Agarwal, Ashok (Wiley-Blackwell, 2020)Oxidative stress (OS) is characterised by an excessive amount of reactive oxygen species (ROS) which negatively affect sperm functions. In this study, the influence of leucocytes on seminal oxidation–reduction potential ... -
Sperm morphology assessment in the era of intracytoplasmic sperm injection: Reliable results require focus on standardization, quality control, and training
Agarwal, Ashok; Sharma, Rakesh; Henkel, Ralf (Korean Society for Sexual Medicine and Andrology, 2021)Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines, semen analysis ... -
Utility of Antioxidants in the Treatment of Male Infertility: Clinical Guidelines Based on a Systematic Review and Analysis of Evidence
Agarwal, Ashok; Leisegang, Kristian (The world journal of men's health, 2021)It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants could have a significant role in the treatment of male infertility. The main objectives ... -
The validity and reliability of computer-aided semen analyzers in performing semen analysis: a systematic review
Leisegang, Kristian; Agarwal, Ashok; Renata, Finelli (Translational Andrology and Urology., 2021)Background: Computer-aided sperm analyzers (CASA) are currently used worldwide for semen analysis. However, there are doubts about their reliability to fully substitute the human operator. Therefore, this study aimed to ...