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Diagnostic value of advanced semen analysis in evaluation of male infertility
(Blackwell Publishing Ltd, 2021)
Conventional semen analysis is the standard of care to initially evaluate the fertility status of a male patient. However, it has some limitations and among these are failure to correctly identify the aetiology underlying ...
A Global Survey of Reproductive Specialists to Determine the Clinical Utility of Oxidative Stress Testing and Antioxidant Use in Male Infertility
(The world journal of men's health, 2021)
Globally, infertility impacts 15% of couples trying to conceive. The incidence of male infertility has been increasing over the past several decades, ranging from 20% to 70% worldwide [1,2]. The male partner is found to ...
Comparative analysis of tests used to assess sperm chromatin integrity and DNA fragmentation
(Blackwell Publishing Ltd, 2021)
Male infertility has a complex etiology, and many times, the cause is unknown. While routine semen analysis provides an overview of basic semen parameters, such as sperm concentration, motility, viability and morphology, ...
Evaluation of seminal oxidation–reduction potential in male infertility
(Blackwell Publishing Ltd, 2021)
The role of oxidative stress in male infertility has been broadly recognised, and the search for a new marker to determine the redox environment in semen has gained considerable interest. Oxidation–reduction potential (ORP) ...
Reactive oxygen species in male reproduction: A boon or a bane?
(Blackwell Publishing Ltd, 2021)
Reactive oxygen species (ROS) are free radicals derived from oxygen during normal cellular metabolism. ROS play a crucial role in the physiological processes and signalling pathways associated with male fertility. At ...
Total antioxidant capacity—Relevance, methods and clinical implications
(Blackwell Publishing Ltd, 2021)
Oxidative stress is pre-empted by an adequate level of antioxidants, which scavenge oxidants when they are produced in excess by different sources, including leukocytes and immature spermatozoa. Enzymatic antioxidants, ...
Male infertility, oxidative stress and antioxidants
(IntechOpen, 2021)
Within the male reproductive system, oxidative stress (OS) has been identified
as prevailing etiology of male infertility. The effects of reactive oxygen species
(ROS) on male fertility depend on the dimensions, “modus ...
Utility of Antioxidants in the Treatment of Male Infertility: Clinical Guidelines Based on a Systematic Review and Analysis of Evidence
(The world journal of men's health, 2021)
It is widely accepted that oxidative stress plays an important role in the pathophysiology of male infertility and that antioxidants
could have a significant role in the treatment of male infertility. The main objectives ...
The sixth edition of the WHO manual for human semen analysis: A critical review and SWOT analysis
(MDPI, 2021)
Semen analysis is the cornerstone of male fertility evaluation with WHO guidelines
providing the basis for procedural standardization and reference values worldwide. The first WHO
manual was published in 1980, and five ...