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K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
(Frontiers, 2019-05-24)
Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ...
Measuring Streptococcus mutans, Streptococcus sanguinis and Candida albicans biofilm formation using a real-time impedance-based system
(Elsevier, 2019-12-20)
Candida albicans and streptococci are amongst the most common fungal and bacterial organisms present in the
oral cavity, with a growing body of evidence implicating C. albicans in increased caries severity and in ...
Colistin, Carbapenem and Cephalosporin-resistant Klebsiella pneumoniae reported from Misrata, Libya
(Medpharm Publications, 2017)
Background: National surveillance of antimicrobial resistance has become a mandatory approach to control the spread of antimicrobial resistance and for the establishment of antibiotic treatment guidelines. In this study, ...
Candida species carriage in diabetic patients in Misrata, Libya
(Medpharm Publications, 2017)
Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ...
Vitek characterisation of type 2 diabetes-associated Candida species
(Elsevier, 2017)
Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...
Real-time assessment of Candida biofilm formation
(Elsevier, 2021-09)
Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, particularly when the Candida biofilm is composed of drug-resistant species. Although the biofilm formation ...
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
(AIMS Press, 2021-09-10)
The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients ...
Real-time assessment of Candida biofilm disruption by Galenia africana
(2022-05-25)
Candida species often cause opportunistic infections in immunocompromised patients and are able to form highly structured biofilms that protect the yeast cells from the external environment and the action of antimicrobials. ...