Medical Bioscience: Recent submissions
Now showing items 1-20 of 293
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Role of oxidative stress in male infertility
(Bioscientifica Ltd, 2023)Infertility affects millions of couples worldwide. Oxidative stress (OS) causes peroxidation of lipids and damage to spermatozoa, thus, reducing the quality of seminal parameters. In addition, the differences in the levels ... -
Effects of Profortil on Leptin-Induced Adverse Effects onSperm Parameters in Sprague-Dawley Rats
(PubMed Central Europe PMC, 2024)Raised leptin levels induce oxidative stress, which negatively impacts male reproduction. Profortil® is an antioxidant formulation clinically used to improve sperm quality. Whether Profortil® supplementation can prevent ... -
Insights into the Prevalence and Resistance Patterns of Candida Species among Diabetic Patients in Cameroon: Potential Paths for Alternative Treatments
(Science and Education Publishing, 2024-05-06)The study aimed to fill the knowledge gap regarding the prevalence of Candida infections in diabetic patients and their sensitivity to antifungal drugs. Clinical samples from diabetic patients were collected at Yaoundé ... -
Aqueous extractions of Mondia whitei root improve human sperm function in vitro
(Elsevier B.V., 2024)Introduction: Mondia whitei (Mw) is a prominent African medicinal plant that is widely used as traditional treatment in the management of sexual dysfunction and male infertility. Yet, there is a paucity of scientific ... -
SARS-CoV-2 spike protein diversity at an intra-host level, among SARS-CoV-2 infected individuals in South Africa, 2020 to 2022
(Public Library of Science, 2023)Intra-host diversity studies are used to characterise the mutational heterogeneity of SARSCoV-2 infections in order to understand the impact of virus-host adaptations. This study investigated the frequency and diversity ... -
A new fluorescent method to determine honey bee sperm motility parameters with computer-aided sperm analysis
(Taylor and Francis Ltd., 2023)Honey bees are a keystone species, playing an important role in the food cycle. Improving honey bee reproduction will aid in the replacement of lost colonies. Fertility potential and reproductive health are dependent on ... -
Black tea aqueous extracts improve human sperm functions: an in vitro study
(Wiley-Hindawi, 2023)Infertility affects about 25% of couples worldwide, and oxidative stress (OS) is linked to its idiopathic etiology. Green, black, white, and oolong teas are produced from Camellia sinensis, depending on their oxidation ... -
Improving productivity and soil fertility in Medicago sativa and Hordeum marinum through intercropping under saline conditions
(BioMed Central Ltd, 2024)Background and aims: Intercropping is an agriculture system used to enhance the efficiency of resource utilization and maximize crop yield grown under environmental stress such as salinity. Nevertheless, the impact of ... -
Histomorphometric changes in testis following administration of tenofovir nanoparticles in an animal model
(Springer, 2024)Background: Nanoparticle-based drugs are new inventions in the management of the Human immunodeficiency virus (HIV) pandemic, especially resistant forms of the virus in anatomical sanctuary sites and organs such as the ... -
Aqueous extractions of mondia whitei root improve human sperm function in vitro
(Elsevier B.V., 2024)Introduction: Mondia whitei (Mw) is a prominent African medicinal plant that is widely used as traditional treatment in the management of sexual dysfunction and male infertility. Yet, there is a paucity of scientific ... -
Frequency, kinetics and determinants of viable SARS-cov-2 in bioaerosols from ambulatory COVID-19 patients infected with the beta, delta or omicron variants
(Nature Research, 2024)Airborne transmission of SARS-CoV-2 aerosol remains contentious. Importantly, whether cough or breath-generated bioaerosols can harbor viable and replicating virus remains largely unclarified. We performed size-fractionated ... -
Antioxidant, anti-diabetic, and anti-inflammation activity of Garcinia livingstonei aqueous leaf extract: a preliminary study
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Diabetes mellitus (DM) is the second leading cause of mortality globally. The increased concern for DM is due to the underlying complications accompanying hyperglycaemia, associated with oxidative stress and consequent ... -
Green synthesis of gold nanoparticles using liquiritin and other phenolics from Glycyrrhiza glabra and their anti-Inflammatory activity
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)Phenolic compounds are the main phytochemical constituents of many higher plants. They play an important role in synthesizing metal nanoparticles using green technology due to their ability to reduce metal salts and stabilize ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in SH-SY5Y cells
(Elsevier B.V., 2024)Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. The pathological hallmarks of PD are defined by the loss of dopaminergic neurons in the substantia nigra pars compacta ... -
The impact of mitochondrial impairments on sperm function and male fertility: a systematic revie
(BMC, 2024)Background Besides adenine triphosphate (ATP) production for sustaining motility, the mitochondria of sperm also host other critical cellular functions during germ cell development and fertilization including calcium ... -
Biosensors as early warning detection systems for waterborne cryptosporidium
(IWA Publishing, 2023)Waterborne disease is a global health threat contributing to a high burden of diarrhoeal disease, and growing evidence indicates a prospective increase in incidence coinciding with the profound effects of climate change. ... -
The impact of mitochondrial impairments on sperm function and male fertility: a systematic review
(University of the Western Cape, 2024)Background Besides adenine triphosphate (ATP) production for sustaining motility, the mitochondria of sperm also host other critical cellular functions during germ cell development and fertilization including calcium ... -
Evaluation of synergistic anticandidal activity of galenia africana extract and fluconazole against candida albicans and candida glabrata
(Elsevier, 2022-03)Candida infections have increased in recent years and are causing a serious public health concern. In addition, Candida species are becoming resistant to numerous antifungal drugs. It is for this reason that alternative ... -
Overview of the effects of moringa oleifera leaf extract on oxidative stress and male infertility: a review
(MDPI, 2023)According to a recent report by the WHO, 50–80 million people suffer with infertility. Amongst these populations, male counterparts account for 20–50% of infertility cases. The aetiology of infertility in men includes many ... -
Controversy and consensus on indications for sperm dna fragmentation testing in male infertility: a global survey, current guidelines, and expert recommendations
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of the World Health Organization laboratory manual for the examination and processing of human semen. Many conditions and risk factors ...