Browsing Research Articles (Medical Bioscience) by Title
Now showing items 157-176 of 270
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K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
(Frontiers, 2019-05-24)Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ... -
Leptin deficiency, caused by malnutrition, makes you susceptible to sars-cov-2 infection but could offer protection from severe Covid-19
(American Society for Microbiology, 2021)In much of the developing world, severe malnutrition is the most prevalent cause of immunodeficiency and affects up to 50% of the population in some impoverished communities. As yet, we do not know how severe acute ... -
Life-long programming implications of exposure to tobacco smoking and nicotine before and soon after birth: Evidence for altered lung development
(MDPI, 2011)Tobacco smoking during pregnancy remains common, especially in indigenous communities, and likely contributes to respiratory illness in exposed offspring. It is now well established that components of tobacco smoke, notably ... -
Male infertility
(Lancet Publishing Group, 2021)It is estimated that infertility affects 8–12% of couples globally, with a male factor being a primary or contributing cause in approximately 50% of couples. Causes of male subfertility vary highly, but can be related to ... -
Measuring Streptococcus mutans, Streptococcus sanguinis and Candida albicans biofilm formation using a real-time impedance-based system
(Elsevier, 2019-12-20)Candida albicans and streptococci are amongst the most common fungal and bacterial organisms present in the oral cavity, with a growing body of evidence implicating C. albicans in increased caries severity and in ... -
Medicinal properties and in vitro biological activities of selected helichrysum species from South Africa: A review
(MDPI, 2021)The genus Helichrysum Mill comprises hundreds of species that are mostly flowering perennial shrubs. Some of these plants that belong to the Helichrysum species are used in traditional medicine to treat cough, back pain, ... -
MERS-CoV: Understanding the latest human coronavirus threat
(MDPI, 2018)Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man ... -
Metronidazole in the Prophylaxis and treatment of Anaerobic Infection
(Health and Medical Publishing Group, 1978)The influence of prophylactic metronidazole on vaginal carriage rates of anaerobes and the development of postoperative anaerobic infection was studied in 104 women who underwent abdominal hysterectomy. Metronidazole ... -
Microplastic sources, formation, toxicity and remediation: A review
(Springer, 2023)Microplastic pollution is becoming a major issue for human health due to the recent discovery of microplastics in most ecosystems. Here, we review the sources, formation, occurrence, toxicity and remediation methods of ... -
Microstructurally-based constitutive modelling of the skin – Linking intrinsic ageing to microstructural parameters
(Elsevier, 2018)A multiphasic constitutive model of the skin that implicitly accounts for the process of intrinsic (i.e. chronological) ageing via variation of the constitutive parameters is proposed. The structurally-motivated constitutive ... -
Microtubular dysfunction and male infertility
(Korean Society for Sexual Medicine and Andrology, 2018)Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain ... -
Molecular detection of tick-borne pathogen diversities in ticks from livestock and reptiles along the shores and adjacent islands of lake Victoria and lake Baringo, Kenya
(Frontiers Media, 2017)Tick-borne pathogens (TBPs) are responsible for some of the most serious emerging infectious diseases facing sub-Saharan Africa (SSA) and the rest of the world today (1, 2). In Kenya, TBPs (including viral diseases—arboviruses) ... -
Molecular genetic identification of skeletal remains of apartheid activists in South Africa
(Academic Journals, 2008)The Truth and Reconciliation Commission made significant progress in examining abuses committed during the apartheid era in South Africa. Despite information revealed by the commission, a large number of individuals ... -
Monoclonal Antibodies targeting the HR2 Domain and the region immediately upstream of the HR2 of the S Protein neutralize in Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus
(American Society for Microbiology, 2006)We have previously shown that an Escherichia coli-expressed, denatured spike (S) protein fragment of the severe acute respiratory coronavirus, containing residues 1029 to 1192 which include the heptad repeat 2 (HR2) ... -
Morphological and physiological responses of Calobota sericea plants subjected to water limitation and subsequent rewatering
(Taylor and Francis Group, 2021)Calobota sericea is a native legume of South Africa, confined to the water-limited rangelands, and it has recently been prioritised for additional characterisation regarding its pasture potential. In this study, we examined ... -
Morphometric and structural analysis of Florida manateespermatozoa
(Wiley, 2022)Sperm characteristics, such as sperm morphology and sperm morphometry areimportant in assessing sperm quality. This is especially important for the man-agement and conservation of endangered and exotic species, like the ... -
Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon
(Elsevier, 2014)Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ... -
Muscle fiber type and metabolic profiles of four muscles from the African black ostrich
(Meat Science, 2023)Muscle fiber type, fiber cross-sectional area (CSA), enzyme activities (citrate synthase (CS), 3-hydroxyacetyl Co A dehydrogenase (3HAD), lactate dehydrogenase (LDH) and phosphofructokinase (PFK)) and glycogen content were ... -
The new 6th edition of the WHO laboratory manual for the examination and processing of human semen: Is it a step toward better standard operating procedure?
(Shanghai Institute Materia Medica, 2021)Semen analysis (SA) remains the cornerstone of male infertility evaluation and should ideally be performed by an accredited andrology laboratory or in vitro fertilization (IVF) clinics based on the standards defined ... -
A new fluorescent method to determine honey bee sperm motility parameters with computer-aided sperm analysis
(Taylor and Francis Ltd., 2023)Honey bees are a keystone species, playing an important role in the food cycle. Improving honey bee reproduction will aid in the replacement of lost colonies. Fertility potential and reproductive health are dependent on ...