Browsing Research Articles (Medical Bioscience) by Author "Schoeman, Dewald"
Now showing items 1-4 of 4
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The flexible, extended coil of the pdz-binding motif of the three deadly human coronavirus e proteins plays a role in pathogenicity
Schoeman, Dewald; Cloete, Ruben; Fielding, Burtram C. (MDPI, 2022)The less virulent human (h) coronaviruses (CoVs) 229E, NL63, OC43, and HKU1 cause mild, self-limiting respiratory tract infections, while the more virulent SARS-CoV-1, MERS-CoV, and SARS-CoV-2 have caused severe outbreaks. ... -
Human coronaviruses: counteracting the damage by storm
Schoeman, Dewald; Fielding, Burtram C. (MDPI Viruses, 2021)Over the past 18 years, three highly pathogenic human (h) coronaviruses (CoVs) have caused severe outbreaks, the most recent causative agent, SARS-CoV-2, being the first to cause a pandemic. Although much progress has been ... -
Is there a link between the pathogenic human Coronavirus envelope protein and immunopathology? A review of the literature
Fielding, Burtram Clinton; Schoeman, Dewald (Frontiers Media S.A., 2020)Since the severe acute respiratory syndrome (SARS) outbreak in 2003, human coronaviruses (hCoVs) have been identified as causative agents of severe acute respiratory tract infections. Two more hCoV outbreaks have since ... -
Leptin deficiency, caused by malnutrition, makes you susceptible to sars-cov-2 infection but could offer protection from severe Covid-19
Schoeman, Dewald; Fielding, Burtram C. (American Society for Microbiology, 2021)In much of the developing world, severe malnutrition is the most prevalent cause of immunodeficiency and affects up to 50% of the population in some impoverished communities. As yet, we do not know how severe acute ...