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A novel cell-based binding assay system reconstituting interaction between SARS-CoV S protein and its cellular receptor
(Elsevier, 2005)
Severe acute respiratory syndrome (SARS), a life-threatening disease, is caused by the newly identified virus SARS coronavirus (SARSCoV).
In order to study the spike (S) protein of this highly contagious virus, we established ...
Monoclonal Antibodies targeting the HR2 Domain and the region immediately upstream of the HR2 of the S Protein neutralize in Vitro Infection of Severe Acute Respiratory Syndrome Coronavirus
(American Society for Microbiology, 2006)
We have previously shown that an Escherichia coli-expressed, denatured spike (S) protein fragment of the
severe acute respiratory coronavirus, containing residues 1029 to 1192 which include the heptad repeat 2
(HR2) ...