Research Articles (Medical Bioscience): Recent submissions
Now showing items 21-40 of 256
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Real-time assessment of interspecies candida biofilm formation
(Bentham Open, 2022-12-30)Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, with Candida having the ability to form highly structured biofilms that protect them from the external ... -
Cytotoxic and cell cycle arrest properties of two steroidal alkaloids isolated from Holarrhena floribunda (G. Don) T. Durand & Schinz leaves
(BMC, 2019)The plant Holarrhena floribunda (H. floribunda; G. Don) is indigenous to sub-Saharan Africa and is traditionally used to treat several ailments. The present study was carried out to isolate and characterize bioactive ... -
Human coronavirus NL63: A clinically important virus?
(Future Science Group, 2011)Respiratory tract infection is a leading cause of morbidity and mortality worldwide, especially among young children. Human coronaviruses (HCoVs) have only recently been shown to cause both lower and upper respiratory tract ... -
The effectiveness of sewage treatment processes to remove faecal pathogens and antibiotic residues
(TAYLOR & FRANCIS INC, 2013)Pathogens and antibiotics enter the aquatic environment via sewage effluents and may pose a health risk to wild life and humans.The aim of this study was to determine the levels of faecal bacteria, and selected antibiotic ... -
Further evidence for periodontal disease as a risk indicator for adverse pregnancy outcomes
(Elsevier, 2017)Although there is increasing evidence to suggest an association between periodontal disease and adverse pregnancy outcomes, the issue remains controversial. Study objective: This study tested the hypothesis that ... -
Is human immunodeficiency virus (HIV) stage an independent risk factor for altering the periodontal status of HIV-positive patients? A South African study
(BMC, 2013)The immunosuppresion in HIV patients makes them highly susceptible to microbial infections. The aim of the study was to establish whether HIV stage (as depicted by CD4+ T lymphocyte counts) could independently be associated ... -
The effects of endocrine disrupting chemicals on biomarkers of inflammation produced by lipopolysaccharide stimulated raw264.7 macrophages
(MDPI, 2019)Endocrine disrupting chemicals (EDCs) are common pollutants in the environment and can induce disruption of the endocrine and immune systems. The present study evaluated the effects of selected common environmental EDCs ... -
Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis
(Korean Society for Sexual Medicine and Andrology, 2023)Purpose: Despite the significant role of varicocele in the pathogenesis of male infertility, the impact of varicocele repair (VR) on conventional semen parameters remains controversial. Only a few systematic reviews and ... -
Human coronavirus research: 20 years since the SARS-CoV outbreak
(Frontiers Media, 2022)This Editorial introduces 10 articles published in a Special Issue highlighting human coronavirus (hCoV) research on the twentieth anniversary of the outbreak of severe acute respiratory syndrome (SARS) in late 2002. ... -
Impact of body composition analysis on male sexual function: A metabolic age study
(Frontiers Media, 2023)Metabolic Age (MetAge) and body composition analysis may reflect an individual’s metabolic status, which is believed to influence male sexual and gonadal functions. Although erectile dysfunction (ED) and hypogonadism ... -
Face-to-face versus online-based lectures: A covid-19 induced study on assessments
(Frontiers Media, 2022)There is much debate regarding the impact of COVID-induced lockdown on the standard of assessments, mainly since students were assessed at home via an online assessment platform. Regular orthodox lectures and assessments ... -
Next generation precision medicine: Crispr-mediated genome editing for the treatment of neurodegenerative disorders
(Springerlink, 2019)Despite significant advancements in the field of molecular neurobiology especially neuroinflammation and neurodegeneration, the highly complex molecular mechanisms underlying neurodegenerative diseases remain elusive. As ... -
The impact of dose rate on dna double-strand break formation and repair in human lymphocytes exposed to fast neutron irradiation
(MDPI, 2019)first_pagesettingsOrder Article Reprints Open AccessArticle The Impact of Dose Rate on DNA Double-Strand Break Formation and Repair in Human Lymphocytes Exposed to Fast Neutron Irradiation by Shankari Nair 1,2,*,Monique ... -
Tunel assay: establishing a sperm dna fragmentation cut-off value for Egyptian infertile men
(Wiley Online Library, 2019)Male factor infertility is responsible for half of all infertility cases. Conventional semen analysis is inadequate to evaluate male fertility. Sperm DNA fragmentation (SDF) test can be done by: direct methods such as ... -
Is there plagiarism in the most influential publications in the field of andrology?
(Wiley Online Library, 2019)Plagiarism is a common form of academic misconduct that extensively jeopardises the quality of scientific publication. The purpose of this study is to determine the extent of plagiarism in the most influential andrology ... -
Green tea (Camellia sinensis) aqueous extract improved human spermatozoa functions in vitro
(ResearchGate, 2022)Background: Idiopathic causes of infertility is associated with oxidative stress. Antioxidants are known to scavenge the excessive production of reactive oxygen species (ROS). Green tea (Camellia sinensis) contains polyphenols ... -
Automation of human semen analysis using a novel artificial intelligence optical microscopic technology
(Wiley Online Library, 2019)Current semen analysis still commonly depends on a manual microscopy method in clinical laboratories worldwide. However, some of the major disadvantages of this technique are that it is labour‐intensive, subjective, ... -
The stability and anti-angiogenic properties of titanium dioxide nanoparticles (tio2nps) using caco-2 cells
(MDPI, 2022)Titanium dioxide nanoparticles (TiO2NPs) are found in a wide range of products such as sunscreen, paints, toothpaste and cosmetics due to their white pigment and high refractive index. These wide-ranging applications ... -
The effects of silver nanoparticles on RAW 264.7. Macrophages and human whole blood cell cultures
(University of the Western Cape, 2019)Silver nanoparticles (AgNPs) are commonly found in consumer products due to their antimicrobial properties. This study evaluated the effects of AgNPs on the murine macrophage cell line RAW 264.7 and human whole blood cell ... -
Exosomes form tunneling nanotubes (TUNTs) in the blood-brain barrier: A nano-anatomical perspective of barrier genesis
(Frontiers Media, 2022)The blood-brain barrier (BBB) is a robust interface between the blood and the central nervous system. Barrier type endothelium is able to limit paracellular (PC) movement, relegating molecular flux to the transendothel ...