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Now showing items 11-19 of 19
Evolution and structural analysis of Glossina morsitans (Diptera; Glossinidae) Tetraspanins
(MDPI, Basel, Switzerland, 2014)
Tetraspanins are important conserved integral membrane proteins expressed in
many organisms. Although there is limited knowledge about the full repertoire, evolution and structural characteristics of individual members ...
Inferring bona fide transfrags in RNA-Seq derived-transcriptome assemblies of non-model organisms
(BioMed Central, 2015)
Background: De novo transcriptome assembly of short transcribed fragments (transfrags) produced from sequencing-by-synthesis technologies often results in redundant datasets with differing levels of unassembled, partially ...
Molecular evolution of key receptor genes in primates and non-human primates
(Science Publishing Group, 2014)
African primates remain an unexplored source of information required to complete the origin and evolution of many human pathogens. Current studies have shown the importance of several receptor human genes implicated in ...
A glance at quality score: implication for de novo transcriptome reconstruction of Illumina reads
(Frontiers, 2014)
Downstream analyses of short-reads from next-generation sequencing platforms are often preceded by a pre-processing step that removes uncalled and wrongly called bases. Standard approaches rely on their associated base ...
Transcriptomics of the Rooibos (Aspalathus linearis) Species Complex
(MDPI, 2020)
Rooibos (Aspalathus linearis), widely known as a herbal tea, is endemic to the Cape Floristic Region of South Africa (SA). It produces a wide range of phenolic compounds that have been associated with diverse health-promoting ...
Capacity building for whole genome sequencing of Mycobacterium tuberculosis and bioinformatics in high TB burden countries
(Oxford University Press, 2020)
Background
Whole-genome sequencing (WGS) is increasingly used for Mycobacterium tuberculosis (Mtb) research. Countries with the highest tuberculosis (TB) burden face important challenges to integrate WGS into surveillance ...
Genome-wide SNP identification by high-throughput sequencing and selective mapping allows sequence assembly positioning using a framework genetic linkage map
(BioMed Central, 2010)
Determining the position and order of contigs and scaffolds from a genome assembly within an organism’s genome remains a technical challenge in a majority of sequencing projects. In order to exploit contemporary technologies ...
Gonad differentiation in zebrafish is regulated by the canonical Wnt signalling pathway
(Society for the Study of Reproduction, 2014)
Zebrafish males undergo a ‘‘juvenile ovary-to-testis’’ gonadal transformation process. Several genes, including nuclear receptor subfamily 5, group A (nr5a) and anti-Mu¨ llerian hormone (amh), and pathways such as Tp53-mediated ...
DAMPD: a manually curated antimicrobial peptide database
(Oxford University Press, 2012)
The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates ...