Faculty of Natural Sciences: Recent submissions
Now showing items 2161-2180 of 2662
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Potential broad spectrum inhibitors of the coronavirus 3CLpro: A virtual screening and structure-based drug design study
(MDPI, 2015)Human coronaviruses represent a significant disease burden; however, there is currently no antiviral strategy to combat infection. The outbreak of severe acute respiratory syndrome (SARS) in 2003 and Middle East respiratory ... -
Effect of the metabolic syndrome on male reproductive function: a case-controlled pilot study
(Wiley, 2014)The metabolic syndrome (MetS) is a constellation of various risk factors. This study aimed to investigate the effect of MetS on testosterone and progesterone, and semen parameters, in a case-controlled pilot study. Male ... -
Reviewing evidence of marine ecosystem change off South Africa
(National Inquiry Services Centre, 2013)Recent changes have been observed in South African marine ecosystems. The main pressures on these ecosystems are fishing, climate change, pollution, ocean acidification and mining. The best long-term datasets are for trends ... -
Platinum overlaid PdCulr/C: an Improved Methanol Oxidation Elextrocatalyst
(ESG, 2013)A platinum overlaid PdCuIr/C (Pt-PdIrCu/C) anodic catalyst for direct methanol fuel cell was prepared by a two-step reduction method. Transmission electron microscopy (TEM) and X-ray diffraction (XRD) results show that the ... -
Revealing the cold dust in low-metallicity environments: I. Photometry analysis of the Dwarf Galaxy Survey with Herschel
(EDP Sciences, 2013)Context. We present new photometric data from our Herschel Guaranteed Time Key Programme, the Dwarf Galaxy Survey (DGS), dedicated to the observation of the gas and dust in low-metallicity environments. A total of 48 ... -
Blood pressure gradients and cardiovascular risk factors in urban and rural populations in Abia State South Eastern Nigeria using the WHO STEPwise approach
(Public Library of Science, 2013)Background: Developing countries of sub-Saharan Africa (SSA) face a double burden of non-communicable diseases (NCDs) and communicable diseases. As high blood pressure (BP) is a common global cardiovascular (CV) disorder ... -
An unconditionally stable nonstandard finite difference method applied to a mathematical model of HIV infection
(De Gruyter Open, 2013)We formulate and analyze an unconditionally stable nonstandard finite difference method for a mathematical model of HIV transmission dynamics. The dynamics of this model are studied using the qualitative theory of dynamical ... -
Existence domains of dust-acoustic solitons and supersolitons
(AIP PublishingAIP Publishing, 2013)Using the Sagdeev potential method, the existence of large amplitude dust-acoustic solitons and supersolitons is investigated in a plasma comprising cold negative dust, adiabatic positive dust, Boltzmann electrons, and ... -
Amorphous Pt@dCu/CNT catalyst for methanol elextrooxidation
(South African Chemical Institute (SACI), 2013)A multi-walled carbon nanotube-supported, Pt decorated nano-sized amorphous PdCu alloy cores (denoted as Pt@PdCu/CNT) catalyst with lower Pt loading is synthesized via a galvanic displacement reaction. The structure is ... -
Trends in Genotypic HIV-1 Antiretroviral resistance between 2006 and 2012 in South African Patients receiving first- and second line antiretroviral treatment regimens
(University of the Western CapePublic Library of Science -- PLoS, 2013)South Africa's national antiretroviral (ARV) treatment program expanded in 2010 to include the nucleoside reverse transcriptase (RT) inhibitors (NRTI) tenofovir (TDF) for adults and abacavir (ABC) for children. We ... -
A diverse array of genetic factors contribute to the pathogenesis of Systemic Lupus Erythematosus
(Biomed Central, 2013)Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with variable clinical presentation frequently affecting the skin, joints, haemopoietic system, kidneys, lungs and central nervous system. It can ... -
Self-catalytic growth of tin oxide nanowires by chemical vapor deposition process
(Hindawi, 2013)We report on the synthesis of tin oxide (SnO2) nanowires by a chemical vapor deposition (CVD) process. Commercially bought SnO nanopowders were vaporized at 1050∘C for 30 minutes with argon gas continuously passing through ... -
Molecular adaptation mechanisms employed by ethanologenic bacteria in response to lignocellulose-derived inhibitory compounds
(Ivyspring, 2013)Current international interest in finding alternative sources of energy to the diminishing supplies of fossil fuels has encouraged research efforts in improving biofuel production technologies. In countries which lack ... -
Hot subdwarf stars in close-up view IV. Helium abundances and the 3He isotopic anomaly of subdwarf B stars
(EDP Sciences, 2013)Atmospheric parameters and helium abundances of 44 bright subdwarf B stars have been determined. More than half of our sample consists of newly discovered stars from the Edinburgh Cape survey. We showed that effective ... -
Aptameric recognition-modulated electroactivity of poly(4-styrenesolfonic acid)-doped polyaniline films for single-shot detection of tetrodotoxin
(MDPI, 2015)The work being reported is the first electrochemical sensor for tetrodotoxin (TTX). It was developed on a glassy carbon electrodes (C) that was modified with poly(4-styrenesolfonic acid)-doped polyaniline film (PANI/PSSA). ... -
Testing of eight medicinal plant extracts in combination with kresoxim-methyl for integrated control of botrytis cinerea in apples
(MDPI, 2015)Botrytis cinerea is a fungus that causes gray mold on many fruit crops. Despite the availability of a large number of botryticides, the chemical control of gray mold has been hindered by the emergence of resistant strains. ... -
Effect of ni core structure on the electrocatalytic activity of pt-ni/c in methanol oxidation.
(MDPI, 2013)Methanol oxidation catalysts comprising an outer Pt-shell with an inner Ni-core supported on carbon, (Pt-Ni/C), were prepared with either crystalline or amorphous Ni core structures. Structural comparisons of the two forms ... -
Exploration of scaffolds from natural products with antiplasmodial activities, currently registered antimalarial drugs and public malarial screen data
(MDPI, 2016)In light of current resistance to antimalarial drugs, there is a need to discover new classes of antimalarial agents with unique mechanisms of action. Identification of unique scaffolds from natural products with in vitro ... -
Candida antifungal drug resistance in sub-Saharan African populations: A systematic review
(Science Navigation Group, 2017)BACKGROUND: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV ... -
Bacterial morphotype grading for periodontal disease assessment
(Nature Publishing Group, 2017)BACKGROUND: Listgarten and Hellden (1978) used darkfield microscopy of wet mounts to differentiate between healthy and periodontally diseased sites in the mouth by expressing the different bacterial morphotypes observed ...