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Inequalities in the prevalence of stunting, anemia and exclusive breastfeeding among African children
(BMC, 2022)
Childhood stunting and anemia are on the increase in many resource-constrained settings, without
a counter increase in proper feeding practices such as exclusive breastfeeding. The objective of this study was to
explore ...
Time trends in Tuberculosis mortality across the BRICS: An age-period-cohort analysis for the GBD 2019
(Elsevier, 2022)
There were 549,522 tuberculosis deaths across the BRICS in 2019, accounting for 39.3% of global deaths.
Among HIV-negative populations, the age-standardised mortality rate (ASMR) of tuberculosis in BRICS remained
far ...
Critical appraisal of clinical guidelines for prevention and management of doxorubicin-induced cardiotoxicity
(Journal of Oncology Pharmacy Practice, 2022)
Objective: Doxorubicin is a valuable chemotherapeutic drug; however, it is associated with a high risk of cardiotoxicity. Several institutions and organizations have developed guidelines for risk factor assessment, monitoring, ...
Strategies for malaria vaccination during the Covid-19 pandemic in African countries
(World Health Organization, 2022)
Since October 2021, the World Health
Organization (WHO) recommends the
use of RTS,S/AS01 (RTS,S) malaria vaccine for children in areas of moderate
to high transmission of Plasmodium
falciparum in Africa.1
The vaccine ...
Challenges faced by African healthcare workers during the third wave of the pandemic
(Wiley, 2022)
Africa experienced the third wave of the coronavirus disease in 2019, which caused
an 18% rise in cases in most parts of the continent. As of January 2022, the region
had an estimated 10.4 million cumulative cases and ...
Treating urinary tract infections in public sector primary healthcare facilities in Cape Town, South Africa: A pharmaceutical perspective
(South African Medical Association, 2022)
Antibiotic resistance is a global healthcare burden complicating the management of infections. Urinary tract infections (UTIs) are commonly treated in primary care. Managing UTIs appropriately in primary care can combat ...
The validation of a simple, robust, stability-indicating rp-hplc method for the simultaneous detection of lamivudine, tenofovir disoproxil fumarate, and dolutegravir sodium in bulk material and pharmaceutical formulations
(Hindawi, 2022)
An effective analytical method is requisite to ensure the accurate identification and quantification of drug(s), either in bulk
material or in complex matrices, which form part of finished pharmaceutical products. For the ...
Sub-analysis of cyp-guides data: Assessing the prevalence and impact of drug-gene interactions in an ethnically diverse cohort of depressed individuals
(Frontiers Media, 2022)
Minority groups are underrepresented in pharmacogenomics (PGx)
research. Recent sub-analysis of CYP-GUIDES showed reduced length of stay (LOS)
in depressed patients with CYP2D6 sub-functional status. Our primary objective ...
Comparative study on the topical and transdermal delivery of diclofenac incorporated in nano-emulsions, nano-emulgels, and a colloidal suspension
(Springer, 2022)
Transdermal delivery of active pharmaceutical ingredients (APIs) can be challenging, since the skin possesses a rate-limiting barrier, which may be overcome when APIs possess certain ideal physicochemical properties. The ...
Proprotein convertase subtilisin/kexin type 9 genetic screening using the vervet (Chlorocebus aethiops) model
(Journal of Medical Primatology, 2022)
Background: The proprotein convertase subtilisin/kexin type 9 (PCSK9) gene has come to prominence due to its reported function in the clearance of low-density li-poprotein cholesterol. The vervet monkey (Chlorocebus ...