Browsing Research Articles (Biotechnology) by Author "Aruleba, Raphael Taiwo"
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Applications of computational methods in biomedical breast cancer imaging diagnostics: A review
Aruleba, Kehinde; Obaido, George; Aruleba, Raphael Taiwo (Multidisciplinary Digital Publishing Institute (MDPI), 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ... -
In silico prediction of new antimicrobial peptides and proteins as druggable targets towards alternative anti-schistosomal therapy
Aruleba, Raphael Taiwo; Tincho, Marius Belmondo; Pretorius, Ashley (Elsevier, 2021)Schistosomiasis is a debilitating disease caused by a parasitic flatworm found in fresh- water. With the exponential increase in prevalence, Praziquantel (PZQ) remains the only effective treatment drug, however, resistance ... -
Inhibitory potential of repurposed drugs against the SARS-CoV-2 main protease: A computational-aided approach
Fadaka, Adewale Oluwaseun; Aruleba, Raphael Taiwo; Sibuyi, Nicole Remaliah Samantha (Taylor and Francis, 2020)The exponential increase in cases and mortality of coronavirus disease (COVID-19) has called for a need to develop drugs to treat this infection. Using in silico and molecular docking approaches, this study investigated ... -
PZQ Therapy: How close are we in the development of effective alternative anti-schistosomal drugs?
Aruleba, Raphael Taiwo; Adekiya, Tayo Alex; Pretorius, Ashley (Bentham Science Publishers, 2019)Today schistosomiasis, caused mainly by the three major schistosome species (S. mansoni, S. haematobium and S. japonicum), has for many decades and still continues to be on a rapid and swift rise globally, claiming ...