Browsing by Subject "Antiretroviral therapy"
Now showing items 1-20 of 25
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The co-occurrence of the SAVA syndemic, depression and anxiety as barriers to antiretroviral therapy adherence among Sub-Saharan Africa population groups: A scoping review protocol
(Public Library of Science, 2022)The scale-up of access to antiretroviral therapy has transformed HIV from an acute, terminal disease to a manageable chronic illness. Yet, sustaining high levels of antiretroviral therapy adherence remain a challenge, ... -
Comparing patients’ experiences in three differentiated service delivery models for HIV treatment in South Africa
(SAGE Publications, 2022)Differentiated service delivery for HIV treatment seeks to enhance medication adherence while respecting the preferences of people living with HIV. Nevertheless, patients’ experiences of using these differentiated service ... -
A descriptive study to evaluate the effect of guidelines used by counsellors to improve adherence to antiretroviral therapy in the private sector
(University of the Western Cape, 2006)INTRODUCTION: To achieve a virological outcome to antiretroviral therapy, a high adherence level is required. OBJECTIVE: To implement and evaluate guidelines that will be used by treatment support counsellors in an attempt ... -
The effects of teen clubs on retention in HIV care among adolescents in Windhoek, Namibia
(OpenJournals Publishing AOSIS (Pty) Ltd, 2020)Adolescents living with HIV (ALHIV) are notably underserved by the national HIV programmes globally because of their unique needs. Of particular concern is limited access to and availability of adolescent-friendly ... -
End-user centeredness in antiretroviral therapy services in Nigerian public health facilities
(Medpharm publications, 2014)OBJECTIVE: To describe the perception of end users with regard to end-user centeredness in antiretroviral therapy (ART) service provision in Nigerian public health facilities. DESIGN: A qualitative design was followed. ... -
An exploration of group-based HIV/AIDS treatment and care models in Sub-Saharan Africa using a realist evaluation (Intervention-Context-Actor-Mechanism- Outcome) heuristic tool: a systematic review
(BioMed Central, 2017)Introduction: It is increasingly acknowledged that differentiated care models hold potential to manage large volumes of patients on antiretroviral therapy (ART). Various group-based models of ART service delivery aimed ... -
Factors associated with viral suppression among adolescents on antiretroviral therapy in Free State province, South Africa
(AOSIS, 2022)In 2019, about 1.7 million adolescents between the ages of 10 and 19 years were living with HIV worldwide, of which 170000 were newly infected with HIV in 2019. South Africa has the highest number of persons living with ... -
Gender differences in experiences of ART services in South Africa: a mixed methods study
(Blackwell Publishing Ltd, 2012)Objectives: A mixed methods study exploring gender differences in patient profiles and experiences of ART services, along the access dimensions of availability, affordability and acceptability, in two rural and two urban ... -
HIV-1 diversity and the implementation of integrase strand-transfer inhibitors as part of combination antiretroviral therapy
(SAMA, 2020): The integrase (IN) strand-transfer inhibitor (InSTI) dolutegravir (DTG) is now recommended by the World Health Organization as part of salvage and/or first-line combination antiretroviral therapy (cART).[1] DTG has a ... -
In utero art exposure and birth and early growth outcomes among HIV-exposed uninfected infants attending immunization services: Results from national pmtct surveillance, South Africa
(Oxford University Press, 2017). Despite the recognized benefit of antiretroviral therapy (ART) for preventing and treating HIV, some studies have reported adverse birth outcomes with in utero ART exposure. We evaluated the effect of infant in utero ... -
Interventions for improving treatment outcomes in adolescents on antiretroviral therapy with unsuppressed viral loads: A systematic review protocol
(BMJ Publishing Group, 2021)Adolescents represent one of the most underserved population groups among people living with HIV. With successes in the elimination of mother to child transmission initiatives and advances in paediatric HIV treatment ... -
Molecular dynamic simulations to investigate the structural impact of known drug resistance mutations on HIV-1C integrase-dolutegravir binding
(Public Library of Science, 2020)Resistance associated mutations (RAMs) threaten the long-term success of combination antiretroviral therapy (cART) outcomes for HIV-1 treatment. HIV-1 Integrase (IN) strand transfer inhibitors (INSTIs) have proven to be a ... -
Oral medicine case book 69: Burkitt lymphoma of the oral cavity
(South African Dental Association, 2015)A 25-year-old female was referred to the Haematology Unit at Tygerberg Hospital for further management of a rapidly expanding and large submandibular mass which on fine needle aspiration was suggestive of lymphoma . ... -
Prevalence of oral mucosal lesions in human immunodeficiency virus-infected children attending the Pediatric Infectious Diseases Clinic in Cape Town
(Wiley, 2021)Objective: Investigation of the prevalence of oral mucosal lesions in human immuno-deficiency virus (HIV)-infected children undergoing highly active antiretroviral therapy (HAART).Materials and Methods: Cross-sectional ... -
Promoters and inhibitors of treatment adherence among HIV/AIDS patients receiving antiretroviral therapy in Ghana: Narratives from an underserved population
(Public Library of Science, 2020)Adherence to antiretroviral therapy (ART) is essential to achieving an improved cluster of differentiation-4 (CD4) count, viral load, and quality of life while preventing drug resistance. Medication adherence among people ... -
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ... -
The psychosocial determinants of the intention to test for HIV among young men in KwaZulu-Natal province, South Africa
(Routledge, 2021): Voluntary counselling and testing is one of the effective prevention strategies against the HIV/AIDS epidemic. This study investigated the psychosocial determinants of the intention to be tested for HIV among young men ... -
A realist approach to eliciting the initial programme theory of the antiretroviral treatment adherence club intervention in the Western Cape Province, South Africa
(BioMed Central, 2018)BACKGROUND: The successful initiation of people living with HIV/AIDS on antiretroviral therapy (ART) in South Africa has engendered challenges of poor retention in care and suboptimal adherence to medication. The adherence ... -
Realist evaluation of the antiretroviral treatment adherence club programme in selected primary healthcare facilities in the metropolitan area of Western Cape Province, South Africa: a study protocol
(BMJ, 2016)INTRODUCTION: Suboptimal retention in care and poor treatment adherence are key challenges to antiretroviral therapy (ART) in sub-Saharan Africa. Communitybased approaches to HIV service delivery are recommended to ... -
Reflections of ART policy and its implementation: rebuilding the ship as we sail?
(University of the Free State, 2006)This paper reflects on the early experience with ART implementation in South Africa in the light of the policy goals of increasing ART access whilst improving prevention and strengthening the public health system. It reviews ...