Search
Now showing items 11-20 of 33
Undergraduate antimicrobial stewardship training for pharmacy students: Creating a foundation for containment of antimicrobial resistance in South Africa
(Health and Medical Publishing Group, 2017)
To the Editor: The inappropriate and excessive use of antimicrobial
agents has cultivated the development and progression of antimicrobial
resistance worldwide, which has been recognised as a
threat to global health and ...
FTIR, dissolution and anti-viral activity of nevirapine co-crystals
(OMICS International, 2017)
The study uses Fourier Transform Infrared (FTIR) spectroscopy to identify five Nevirapine (NV) co-crystals,
determines the dissolution profile of the co-crystals and the antiviral activity comparative to pure NV.
Hot ...
Involvement of gamma aminobutyric acid in the anticonvulsant effect of the leaf methanol extract of Ruta graveolens L. (Rutaceae) in mice
(Asian Network for Scientific Information, 2013)
The possible involvement of gamma aminobutyric acid (GABA), in the anticonvulsant effect of Ruta graveolens L. was investigated by studying the effect of the leaf methanol extract against seizures elicited by either ...
Evaluation of the antidiarrhoeal and antidiabetic activities of the leaf aqueous extract of Syzygium cordatum hoscht. ex C.Krauss (Mytraceae) in rodents
(Asian Network for Scientific Information, 2013)
Syzygium cordatum Hoscht. ex C.Krauss is widely used by traditional medicine practitioners to treat many ailments including diarrhoea and diabetes. Despite the folklore use, little evidence can be found in literature to ...
Service learning in pharmacy: Opportunities for student learning and service delivery
(Academic Journals, 2011)
High patient load and understaffing in public health care facilities preclude the provision of optimal
pharmaceutical services in South Africa. A Service Learning in Pharmacy (SLIP) programme for the
University of the ...
The contributions of muscarinic receptors and changes in plasma aldosterone levels to the anti-hypertensive effect of Tulbaghia violacea
(BioMed Central, 2013)
Background: Tulbaghia violacea Harv. (Alliaceae) is used to treat various ailments, including hypertension (HTN) in
South Africa. This study aims to evaluate the contributions of muscarinic receptors and changes in ...
3D-QSAR and docking studies of pentacycloundecylamines at the sigma-1 (σ1) receptor
(Elsevier, 2013)
Pentacycloundecylamine (PCU) derived compounds have been shown to be promising lead structures for the development of novel drug candidates aimed at a variety of neurodegenerative and psychiatric diseases. Here we show for ...
Microwave-assisted methods for the synthesis of pentacyclo[5.4.0.02,6.03,10.05,9]undecylamines
(Elsevier, 2013)
Efficient methodologies for the preparation of pentacyclo[5..4.0.02,6.03,10.05,9]undecane (PCU) amine derivatives are described via microwave-assisted synthesis. The obtained results revealed that microwave-assisted synthetic ...
Direct inhibition of cyclooxygenase-2 enzyme by an extract of Harpagophytum procumbens, harpagoside and harpagide
(Academic Journals, 2011)
A methanolic extract of Harpagophytum procumbens as well as harpagoside and harpagide were tested
as direct inhibitors of cyclooxygenase-2 enzyme (COX-2). The H. procumbens extract demonstrated
direct inhibition (68%) of ...
Acute pharmacokinetics of first line anti-tuberculosis drugs in patients with Pulmonary Tuberculosis and in patients with Pulmonary Tuberculosis co-infected with HIV
(David Publishing, 2011)
The aim of this study was to compare the pharmacokinetics of antituberculosis drugs in patients with
pulmonary tuberculosis (PTB) and in patients with PTB and HIV during the first 24 h of treatment. Designed as a ...