Browsing Medical Bioscience by Subject "Candida"
Now showing items 1-16 of 16
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Candida antifungal drug resistance in sub-Saharan African populations: A systematic review
(Science Navigation Group, 2017)BACKGROUND: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV ... -
Candida species carriage in diabetic patients in Misrata, Libya
(Medpharm Publications, 2017)Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ... -
A comparison of susceptibility patterns of oral Candida isolates from South African and Cameroonian HIV- positive populations
(The International Association for Dental Research (IADR), 2012)METHOD: In this study, Candida isolates were collected from the oral mucosa of 128 South African and 126 Cameroonian HIV-positive patients, by scraping the mouths of consenting patients using sterile cotton swabs. Ethics ... -
Drug susceptibility profiles of Candida species isolated from the oral mucosa of HIV-positive West African patients using the TREK Sensititre system
(2013)BACKGROUND: Candida infections are a common cause of death in immunocompromised patients. The prevalence and anti-mycotic drug susceptibility profiles of Candida species from Cameroon in Africa are unavailable. This ... -
HIV/Candida co-infection in Sub-Saharan African women on ART
(Infectious Diseases Society of Southern Africa, the Sexually Transmitted Diseases Society of Southern and the Public Health Association of South Africa., 2013)INTRODUCTION: Sub-Saharan Africa has 23.5 million cases of HIV and is home to 92% of the world’s HIV-positive pregnant women of whom 24% die of pregnancy related complications. Oral candidiasis is a common condition in ... -
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
(AIMS Press, 2021-09-10)The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients ... -
Insights into the Prevalence and Resistance Patterns of Candida Species among Diabetic Patients in Cameroon: Potential Paths for Alternative Treatments
(Science and Education Publishing, 2024-05-06)The study aimed to fill the knowledge gap regarding the prevalence of Candida infections in diabetic patients and their sensitivity to antifungal drugs. Clinical samples from diabetic patients were collected at Yaoundé ... -
K21 compound, a potent antifungal agent: Implications for the treatment of fluconazole-resistant HIV-associated Candida species
(Frontiers, 2019-05-24)Background/objectives: With mucocutaneous candidiasis being highly prevalent in HIV patients, the emergence of fluconazole-resistant Candida species forms a major challenge in treating and eradicating these infections. The ... -
Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon
(Elsevier, 2014)Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ... -
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ... -
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ... -
Rare fungal species isolated from Libyan diabetic patients
(Infection Control Africa Network (ICAN), 2016)BACKGROUND AND OBJECTIVES: The emerging resistance of Candida species to antifungals routinely used to treat candidiasis in HIV patients and in patients with diabetes mellitus (DM) has resulted in the frequent isolation ... -
Real-time assessment of Candida biofilm formation
(Elsevier, 2021-09)Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, particularly when the Candida biofilm is composed of drug-resistant species. Although the biofilm formation ... -
Real-time assessment of interspecies candida biofilm formation
(Bentham Open, 2022-12-30)Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, with Candida having the ability to form highly structured biofilms that protect them from the external ... -
Strengths and limitations of different Chromogenic Media for the identification of Candida species
(Scientific & Academic Publishing, 2012)The treatment of invasive candidiasis and other Candida infections with the appropriate antifungal agent is assisted by the identification of Candida isolates to the species level. Rapid and accurate methods of differentiation ... -
Vitek characterisation of type 2 diabetes-associated Candida species
(Elsevier, 2017)Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...