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Candida antifungal drug resistance in sub-Saharan African populations: A systematic review
(Science Navigation Group, 2017)
BACKGROUND: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV ...
A comparison of susceptibility patterns of oral Candida isolates from South African and Cameroonian HIV- positive populations
(The International Association for Dental Research (IADR), 2012)
METHOD: In this study, Candida isolates were collected from the oral mucosa of 128 South African and 126 Cameroonian HIV-positive patients, by scraping the mouths of consenting patients using sterile cotton swabs. Ethics ...
Strengths and limitations of different Chromogenic Media for the identification of Candida species
(Scientific & Academic Publishing, 2012)
The treatment of invasive candidiasis and other Candida infections with the appropriate antifungal agent is assisted by the identification of Candida isolates to the species level. Rapid and accurate methods of differentiation ...
Drug susceptibility profiles of Candida species isolated from the oral mucosa of HIV-positive West African patients using the TREK Sensititre system
(2013)
BACKGROUND: Candida infections are a common cause of death in
immunocompromised patients. The prevalence and anti-mycotic
drug susceptibility profiles of Candida species from Cameroon in
Africa are unavailable. This ...
Rare fungal species isolated from Libyan diabetic patients
(Infection Control Africa Network (ICAN), 2016)
BACKGROUND AND OBJECTIVES: The emerging resistance of Candida species to antifungals routinely used to treat candidiasis in HIV patients and in patients with diabetes mellitus (DM) has resulted in the frequent isolation ...
HIV/Candida co-infection in Sub-Saharan African women on ART
(Infectious Diseases Society of Southern Africa, the Sexually Transmitted Diseases Society of Southern and the Public Health Association of South Africa., 2013)
INTRODUCTION: Sub-Saharan Africa has 23.5 million cases of HIV and is home to 92% of
the world’s HIV-positive pregnant women of whom 24% die of pregnancy related
complications. Oral candidiasis is a common condition in ...
Candida species carriage in diabetic patients in Misrata, Libya
(Medpharm Publications, 2017)
Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ...
Vitek characterisation of type 2 diabetes-associated Candida species
(Elsevier, 2017)
Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)
INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ...
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)
Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ...