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Candida antifungal drug resistance in sub-Saharan African populations: A systematic review
(Science Navigation Group, 2017)
BACKGROUND: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV ...
Rare fungal species isolated from Libyan diabetic patients
(Infection Control Africa Network (ICAN), 2016)
BACKGROUND AND OBJECTIVES: The emerging resistance of Candida species to antifungals routinely used to treat candidiasis in HIV patients and in patients with diabetes mellitus (DM) has resulted in the frequent isolation ...
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)
Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ...
Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon
(Elsevier, 2014)
Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ...
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
(AIMS Press, 2021-09-10)
The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients ...