Browsing Research Articles (Biotechnology) by Title
Now showing items 83-102 of 233
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Factors associated with glycemic control among South African adult residents of Mkhondo municipality living with diabetes mellitus
(Lippincott, Williams & Wilkins, 2020)This study examines the rate and the influencing factors of glycemic control among adult residents living with DM in Mkhondo Municipality of South Africa. In this cross-sectional study, 157 individuals attending care for ... -
Factors influencing pigment production by halophilic bacteria and its effect on brine evaporation rates
(Wiley, 2018)The disposal of reject brine, a highly concentrated waste by-product generated by various industrial processes, represents a major economic and environmental challenge. The common practice in dealing with the large ... -
Flavonoid and phenolic acid profiles of dehulled and whole vigna subterranea (l.) Verdc seeds commonly consumed in South Africa
(MDPI, 2022)Bambara groundnut (BGN) is an underexploited crop with a rich nutrient content and is used in traditional medicine, but limited information is available on the quantitative characterization of its flavonoids and phenolic ... -
Forensic parameters and genetic structure based on Y-chromosome short tandem repeats in Lesotho populations
(Forensic Science International: Genetics Supplement Series, 2019)Lesotho is a landlocked country with approximately 2.2 million inhabitants. Over 97% of the population is represented by the Southern Sotho people (Sotho-Tswana group), followed by a number of minorities mostly from the ... -
Forensic science international: genetics supplement series
(ScienceDirect, 2019)We have designed a buffer for preservation of DNA in biological material at room temperature. In this work we evaluated the integrity of DNA from saliva, stored for 4 years and blood stored for 4 months at room temperature. ... -
Functional prediction of candidate micrornas for CRC management using in silico approach
(MDPI, 2019)Approximately 30–50% of malignant growths can be prevented by avoiding risk factors and implementing evidence-based strategies. Colorectal cancer (CRC) accounted for the second most common cancer and the third most common ... -
Fungal‑derived compounds and mycogenic nanoparticles with antimycobacterial activity: a review
(Springer, 2022)Tuberculosis (TB) is a persistent lung infection caused by Mycobacterium tuberculosis. The disease is characterized by high mortality rates of over 1 million per year. Unfortunately, the potency and efectiveness of currently ... -
Gene expression alterations and molecular analysis of CHEK1 in solid tumors
(MDPI, 2020)Alterations in the Checkpoint kinase (CHEK1) gene, its regulation, and the possible clinical outcomes in human solid tumors have not been previously examined. Therefore, the present study was carried out to evaluate the ... -
Gene expression modulation of apoptotic and oestrogen receptor alpha genes by active fractions of selected Nigerian plants on cervical cancer cell line (hela)
(University of Benin, 2021)The roles of natural product in drug discovery and development cannot be over emphasised. It plays a vital role in human therapy and gives a better understanding on the cellular pathways.This study investigated the ... -
Genetic association of solute carrier transporter gene variants with metformin response
(Balkan Journal of Medical Genetics, 2021)Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by elevated blood glucose levels and is influenced by both genetic and environmental factors. It is treated with various classes of oral antidiabetic ... -
Genetic characterisation of Campylobacter concisus: Strategies for improved genomospecies discrimination
(Elsevier, 2021)Although at least two genetically distinct groups, or genomospecies, have been well documented for Campylobacter concisus, no phenotype has yet been identified for their differentiation and thus formal description as ... -
Genetic characterization of the central variable region in African swine fever virus isolates in the Russian federation from 2013 to 2017
(MDPI, 2022)African swine fever virus (ASFV), classified as genotype II, was introduced into Georgia in 2007, and from there, it spread quickly and extensively across the Caucasus to Russia, Europe and Asia. The molecular epidemiology ... -
Genetic diversity, population structure and marker- trait association for 100-seed weight in international safflower panel using silicodart marker information
(MDPI, 2020)Safflower is an important oilseed crop mainly grown in the arid and semi-arid regions of the world. The aim of this study was to explore phenotypic and genetic diversity, population structure, and marker-trait association ... -
Genetic heritage of the Baphuthi highlights an over-ethnicized notion of “Bushman” in the Maloti-Drakensberg, southern Africa
(Cell Press, 2023)Using contemporary people as proxies for ancient communities is a contentious but necessary practice in anthropology. In southern Africa, the distinction between the Cape KhoeSan and eastern KhoeSan remains unclear, as ... -
Genetic landscape of the mitochondrial DNA control region in South African populations
(ScienceDirect, 2019)A high-quality dataset of the mitochondrial DNA control region sequences was generated with Sanger and next-generation sequencing. The study was aimed at characterizing the maternal genetic ancestry and analyzing the ... -
Genetic polymorphisms and haplotypes of the organic cation transporter 1 gene (SLC22A1) in the Xhosa population of South Africa
(Brazilian Society of Genetics, 2014)Human organic cation transporter 1 is primarily expressed in hepatocytes and mediates the electrogenic transport of various endogenous and exogenous compounds, including clinically important drugs. Genetic polymorphisms ... -
Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape
(Springer Science and Business Media B.V., 2023)Background Amphiphilic solute facilitator organic cation transporters mediate the movement of various endogenous and exogenous organic cations, including crucial drugs like metformin, oxaliplatin, and lamivudine. These ... -
Genetic variation and population structure of Botswana populations as identified with AmpFLSTR Identifiler short tandem repeat (STR) loci
(Nature Publishing Group, 2017-07-28)Population structure was investigated in 990 Botswana individuals according to ethno-linguistics, Bantu and Khoisan, and geography (the nine administrative districts) using the Identifiler autosomal microsatellite markers. ... -
Genetic variation in responses to salt stress in Tunisian populations of Medicago ciliaris
(MDPI, 2022)Soil salinity is one of the most serious environmental factors affecting crop productivity around the world. We used a morpho-physiological approach to investigate the salt responses of four Tunisian natural populations ... -
Genome sequences of three vaccine strains and two wild-type canine distemper virus strains from a recent disease outbreak in South Africa
(American Society for Microbiology, 2017)Canine distemper virus causes global multihost infectious disease. This report details complete genome sequences of three vaccine and two new wild-type strains. The wild-type strains belong to the South African lineage, ...