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Now showing items 11-19 of 19
HIV/Candida co-infection in Sub-Saharan African women on ART
(Infectious Diseases Society of Southern Africa, the Sexually Transmitted Diseases Society of Southern and the Public Health Association of South Africa., 2013)
INTRODUCTION: Sub-Saharan Africa has 23.5 million cases of HIV and is home to 92% of
the world’s HIV-positive pregnant women of whom 24% die of pregnancy related
complications. Oral candidiasis is a common condition in ...
Candida species carriage in diabetic patients in Misrata, Libya
(Medpharm Publications, 2017)
Background: There is a paucity of studies describing the prevalence and antimicrobial profiles of Candida in Libya. Limited treatment choices in the antifungal armamentarium in public healthcare settings in Africa require ...
Vitek characterisation of type 2 diabetes-associated Candida species
(Elsevier, 2017)
Background: Type 2 diabetes mellitus (T2DM) predisposes patients to opportunistic infections, such as invasive candidiasis. Treatment of candidiasis is challenged by the emerging resistance of Candida species. In this ...
Proteomic mechanisms of drug resistance in Candida cell membrane fractions
(International Association for Dental Research, 2014)
INTRODUCTION: The African continent has the highest burden of HIV infection, accounting for approximately 65% of new infections globally. Oral candidiasis is a major cause of increased morbidity in HIV-infected individuals ...
Real-time assessment of Candida biofilm formation
(Elsevier, 2021-09)
Background: Candida infections are responsible for increased morbidity and mortality in immunocompromised patients, particularly when the Candida biofilm is composed of drug-resistant species. Although the biofilm formation ...
Proteomics of drug-resistant HIV-associated candidiasis
(University of the Western Cape, 2015)
Candidiasis and HIV co-infection may cause increased patient morbidity and mortality due to oropharyngeal or systemic dissemination. Limited information exists on the prevalence, antifungal susceptibility profiles and drug ...
Multi-drug resistant (MDR) oral Candida species isolated from HIV-positive patients in South Africa and Cameroon
(Elsevier, 2014)
Candida species are a common cause of infection in immune-compromised HIV-positive individuals, who are usually treated with the antifungal drug, fluconazole in public hospitals in Africa. However, information about the ...
HPLC-MS identification and expression of Candida drug-resistance proteins from African HIV-infected patients
(AIMS Press, 2021-09-10)
The objective of this study was to elucidate the proteomic mechanisms of drug resistance in HIV-infected African patients. Cell membrane fractions from forty oral Candida isolates isolated from African HIV-positive patients ...
Real-time assessment of Candida biofilm disruption by Galenia africana
(2022-05-25)
Candida species often cause opportunistic infections in immunocompromised patients and are able to form highly structured biofilms that protect the yeast cells from the external environment and the action of antimicrobials. ...