Biotechnology: Recent submissions
Now showing items 141-160 of 219
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The potential of chalcone-capped gold nanoparticles for the management of diabetes mellitus
(Surfaces and Interfaces, 2021-08)Searching for new natural bioactive capping agents represent an urgent priority in the green synthesis of metal nanoparticles. Additionaly, the biosaftey of metal nanparticles is a major concern especially in medical ... -
The Relationship between Cadmium Toxicity and the Modulation of Epigenetic Traits in Plants
(International Journal of Molecular Sciences, 2021-06)Elevated concentrations of heavy metals such as cadmium (Cd) have a negative impact on staple crop production due to their ability to elicit cytotoxic and genotoxic effects on plants. In order to understand the relationship ... -
PR-1-Like Protein as a Potential Target for the Identification of Fusarium oxysporum: An In Silico Approach
(BioTech, 2021-07)Fusarium oxysporum remains one of the leading causes of economic losses and poor crop yields; its detection is strained due to its presentation in various morphological and physiological forms. This research work sought ... -
The air quality perceptions of the residents of Bayview, Mossel Bay
(NACA, 2014)Background: In developing countries, it often occurs that little attention is given to air pollution emissions due to a lack of proper town planning, household combustion processes, energy production and the continuous ... -
Large Scale Screening of Southern African Plant Extracts for the Green Synthesis of Gold Nanoparticles Using Microtitre-Plate Method
(Molecules, 2016-11)The preparation of gold nanoparticles (AuNPs) involves a variety of chemical and physical methods. These methods use toxic and environmentally harmful chemicals. Consequently, the synthesis of AuNPs using green chemistry ... -
Comparative analysis of responses to field salinity stress in contrasting soybean accessions highlights NaCl exclusion in leaves as a key mechanism for salinity stress tolerance.
(JOURNAL OF OASIS AGRICULTURE AND SUSTAINABLE DEVELOPMENT, 2021)Salinity is one of the main limitations to legume productivity in many regions of the world and it is estimated that 50% of all arable land will become affected by salinity by 2050. The impact of field salinity on soybean ... -
Cheminformatic Characterization of Natural Antimicrob al Products for the Development of New Lead Compounds
(MDPI, 2021)The growing antimicrobial resistance (AMR) of pathogenic organisms to currently pre- scribed drugs has resulted in the failure to treat various infections caused by these superbugs. Therefore, to keep pace with the ... -
Biomedical Relevance of Novel Anticancer Peptides in the Sensitive Treatment of Cancer
(MDPI, 2021)The global increase in cancer mortality and economic losses necessitates the cautious quest for therapeutic agents with compensatory advantages over conventional therapies. Anticancer peptides (ACPs) are a subset of host ... -
Aptamer-Based Diagnostic Systems for the Rapid Screening of TB at the Point-of-Care
(MDPI, 2021)The transmission of Tuberculosis (TB) is very rapid and the burden it places on health care systems is felt globally. The effective management and prevention of this disease requires that it is detected early. Current TB ... -
Improving the functionality of surface-engineered yeast cells by altering the cell wall morphology of the host strain
(Springer, 2021)The expression of functional proteins on the cell surface using glycosylphosphatidylinositol (GPI)-anchoring technology is a promising approach for constructing yeast cells with special functions. The functionality of ... -
PZQ Therapy: How close are we in the development of effective alternative anti-schistosomal drugs?
(Bentham Science Publishers, 2019)Today schistosomiasis, caused mainly by the three major schistosome species (S. mansoni, S. haematobium and S. japonicum), has for many decades and still continues to be on a rapid and swift rise globally, claiming ... -
Prevalence of hypertension and its associated risk factors in a rural black population of Mthatha town,South Africa
(MPDI, 2021)The occurrence of hypertension has been increasing alarmingly in both low and middle-income countries. Despite acknowledging hypertension as the most common life-threatening risk factor for cardiovascular disease (CVD), a ... -
Single nucleotide polymorphisms associated with metformin and sulphonylureas’ glycaemic response among South African adults with type 2 diabetes mellitus
(MDPI, 2021)To examine the association of polymorphisms belonging to SLC22A1, SP1, PRPF31, NBEA, SCNN1B, CPA6 and CAPN10 genes with glycaemic response to metformin and sulphonylureas (SU) combination therapy among South African adults ... -
Investigation of the anti-cancer and apoptotic properties of aqueous extract from fermented African locust bean seeds
(Rynnye Lyan Resources, 2021)Some fermented foods are reported to possess anti-cancer properties. Fermented African locust bean seeds is a condiment prepared from fermentation of Parkia biglobosa. It has been reportedly functional for various medicinal ... -
The macrophage response to mycobacterium tuberculosis and opportunities for autophagy inducing nanomedicines for Tuberculosis therapy
(Frontiers Media S.A., 2021)The major causative agent of tuberculosis (TB), i.e., Mycobacterium tuberculosis (Mtb), has developed mechanisms to evade host defense responses and persist within host cells for prolonged periods of time. Mtb is also ... -
Exogenous 3,3′-diindolylmethane improves vanadium stress tolerance in brassica napus seedling shoots by modulating antioxidant enzyme activities
(MDPI, 2021)3,3′-diindolylmethane (DIM) belongs to a family of indole glucosinolate compounds that have been shown to improve Brassica napus growth through the modulation of reactive oxygen species when applied exogenously. The B. ... -
Expression of cyclin-dependent kinases and their clinical significance with immune infiltrates could predict prognosis in colorectal cancer
(Elsevier, 2021)Introduction: Colorectal cancer (CRC) is one of the most cancer-related mortalities worldwide and remains a major public health issue. Despite several attempts to develop promising therapies for CRC, its survival rate ... -
Draft genome sequence of the putative endophytic bacterium pantoea agglomerans r6, associated with lactuca serriola from South Africa
(American Society for Microbiology, 2021)Here, we present the draft genome sequence (;4.7 Mb) of the endopyhtic bacterium Pantoea agglomerans strain R6, which was isolated from surface-sterilized roots of Lactuca serriola (prickly lettuce) -
Proteomic identification and meta-analysis in salvia hispanica RNA-seq de novo assemblies
(2021)While proteomics has demonstrated its value for model organisms and for organisms with mature genome sequence annotations, proteomics has been of less value in nonmodel organisms that are unaccompanied by genome sequence ... -
Applications of Computational Methods in Biomedical Breast Cancer Imaging Diagnostics: A Review
(MDPI, 2020)With the exponential increase in new cases coupled with an increased mortality rate, cancer has ranked as the second most prevalent cause of death in the world. Early detection is paramount for suitable diagnosis and ...